About this Research Topic
Resiliency is increasingly recognized as a unique mechanism that confers protection during stress. Resilience is not simply the absence of susceptibility but the active process of adapting to stress. Emerging research is only beginning to untangle the neurobiological underpinnings of resiliency – its genetic and developmental origins, the environmental and biological processes that support it, and its life course trajectory. Given that stress is unavoidable across an individual’s lifetime in all species, a foundational understanding of mechanisms underlying individual variability in stress responses – with a focus on the resilient subpopulations – could lead to new treatment and prevention strategies.
This Research Topic aims to bring together a collection of works that tackle the concept of resilience from a wide variety of vantage points, from theoretical to observational to experimental. Examples include but are not limited to: review articles on the neurobiological underpinnings of resilience, perspective pieces on novel experimental designs that better hone in on the relevant mechanisms of resilience, chemogenetic and/or optogenetic dissection of circuits mediating individual variability in stress-responses in rodent models, models of early life experiences promoting long-term resilience, and human observational research centered on defining the behavioral elements, environmental conditions, and individual experiences associated with resilience. In bringing together ideas from multiple animal models and across the lifespan, we hope to elucidate conserved themes across species and unique developmental processes that confer life course resilience, with the ultimate goal of developing novel therapeutic and preventative strategies that enhance resilience.
We welcome submissions that focus on understanding resiliency across species and life course. This includes but is not limited to:
(a) rodent behavioral studies on individual responses to stress
(b) novel behavioral paradigms for resiliency
(c) genetic, epigenetic, molecular, cellular, or circuit level mechanisms of resiliency
(d) wild animal studies on resiliency in a natural environment
(d) behavioral, imaging, or population-specific human studies on resiliency
(e) developmental studies on early life experiences that support future resiliency
(f) studies on the impact of environment and experience across the lifetime on resiliency
Submissions are welcomed in multiple formats, including but not limited to Review articles, Original Research, Perspective, and Methods. Our goal is to bring a highly diverse group of works together to support emergent themes that infuse novel ideas into this relatively new field.
Dr. Dani Dumitriu has received consultation fees from the Society for Neuroscience, has pending consultation fees from Medela, Inc. The Nurture Science Program, of which she is the Director, and has received gift funds from Einhorn Collaborative. Dr. Kristin Anderson has received consultation fees from the Society of Neuroscience. The other Topic Editors declare no competing interests with regards to the Research Topic subject.
This Research Topic aims to bring together a collection of works that tackle the concept of resilience from a wide variety of vantage points, from theoretical to observational to experimental. Examples include but are not limited to: review articles on the neurobiological underpinnings of resilience, perspective pieces on novel experimental designs that better hone in on the relevant mechanisms of resilience, chemogenetic and/or optogenetic dissection of circuits mediating individual variability in stress-responses in rodent models, models of early life experiences promoting long-term resilience, and human observational research centered on defining the behavioral elements, environmental conditions, and individual experiences associated with resilience. In bringing together ideas from multiple animal models and across the lifespan, we hope to elucidate conserved themes across species and unique developmental processes that confer life course resilience, with the ultimate goal of developing novel therapeutic and preventative strategies that enhance resilience.
We welcome submissions that focus on understanding resiliency across species and life course. This includes but is not limited to:
(a) rodent behavioral studies on individual responses to stress
(b) novel behavioral paradigms for resiliency
(c) genetic, epigenetic, molecular, cellular, or circuit level mechanisms of resiliency
(d) wild animal studies on resiliency in a natural environment
(d) behavioral, imaging, or population-specific human studies on resiliency
(e) developmental studies on early life experiences that support future resiliency
(f) studies on the impact of environment and experience across the lifetime on resiliency
Submissions are welcomed in multiple formats, including but not limited to Review articles, Original Research, Perspective, and Methods. Our goal is to bring a highly diverse group of works together to support emergent themes that infuse novel ideas into this relatively new field.
Dr. Dani Dumitriu has received consultation fees from the Society for Neuroscience, has pending consultation fees from Medela, Inc. The Nurture Science Program, of which she is the Director, and has received gift funds from Einhorn Collaborative. Dr. Kristin Anderson has received consultation fees from the Society of Neuroscience. The other Topic Editors declare no competing interests with regards to the Research Topic subject.
Keywords: resilience, neurodevelopment, stress, stress-responses, mechanisms of resiliency, genetic, epigenetic, circuitry, behavior, lifetime
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
