ORIGINAL RESEARCH
Published on 14 Mar 2017
Addressing Adherence Using Genotype-Specific PBPK Modeling—Impact of Drug Holidays on Tamoxifen and Endoxifen Plasma Levels
doi 10.3389/fphar.2017.00067
- 2,424 views
- 5 citations
- Frontiers in Pharmacology
- Experimental Pharmacology and Drug Discovery
- Research Topics
- Bridging the Divide Between Omics Data and Mechanistic Simulations: Frameworks for Interpreting Cancer Progression and Immune Response for Drug Discovery and Development
Bridging the Divide Between Omics Data and Mechanistic Simulations: Frameworks for Interpreting Cancer Progression and Immune Response for Drug Discovery and Development
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Articles
ORIGINAL RESEARCH
Published on 27 Feb 2017
Understanding Physiology in the Continuum: Integration of Information from Multiple -Omics Levels
doi 10.3389/fphar.2017.00091
- 3,498 views
- 14 citations
ORIGINAL RESEARCH
Published on 04 Jan 2017
Inferring the Impact of Regulatory Mechanisms that Underpin CD8+ T Cell Control of B16 Tumor Growth In vivo Using Mechanistic Models and Simulation
doi 10.3389/fphar.2016.00515
- 2,264 views
- 3 citations
REVIEW
Published on 29 Nov 2016
Computational Models of Reactive Oxygen Species as Metabolic Byproducts and Signal-Transduction Modulators
doi 10.3389/fphar.2016.00457
- 5,740 views
- 38 citations
ORIGINAL RESEARCH
Published on 15 Nov 2016
Pharmacodynamic Modeling of Cell Cycle Effects for Gemcitabine and Trabectedin Combinations in Pancreatic Cancer Cells
doi 10.3389/fphar.2016.00421
- 5,290 views
- 29 citations
ORIGINAL RESEARCH
Published on 04 Nov 2016
Machine Perfusion of Porcine Livers with Oxygen-Carrying Solution Results in Reprogramming of Dynamic Inflammation Networks
doi 10.3389/fphar.2016.00413
- 2,469 views
- 15 citations
ORIGINAL RESEARCH
Published on 01 Nov 2016
Dynamic Profiling: Modeling the Dynamics of Inflammation and Predicting Outcomes in Traumatic Brain Injury Patients
doi 10.3389/fphar.2016.00383
- 2,335 views
- 11 citations
ORIGINAL RESEARCH
Published on 27 Sep 2016
Inflammation Following Traumatic Brain Injury in Humans: Insights from Data-Driven and Mechanistic Models into Survival and Death
doi 10.3389/fphar.2016.00342
- 6,092 views
- 39 citations
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Frontiers in Pharmacology
- Experimental Pharmacology and Drug Discovery
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- 23kArticle views
- 7,536Article downloads