Since the past few years, there is increasing evidence that multi-drug resistant pathogens may become more virulent than their antibiotic-suceptible counterparts. This Research Topic will focus on common mechanisms that affect both virulence and antimicrobial resistance. It may include studies where ...
Since the past few years, there is increasing evidence that multi-drug resistant pathogens may become more virulent than their antibiotic-suceptible counterparts. This Research Topic will focus on common mechanisms that affect both virulence and antimicrobial resistance. It may include studies where resistance and virulence share common effectors such as efflux pumps, or studies about global regulatory systems acting on both resistance and virulence (co-regulation). Also of particular interest will be studies about mobile genetic elements such as plasmids or genomic islands that carry both antimicrobial resistance and virulence genes, therefore favoring their co-selection. Studies reporting the co-evolution of antimicrobial resistance and virulence in particular pathogenic clones are also welcome in this Topic.
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