About this Research Topic
The aim of this Research Topic is to point out the mechanisms underlying the pro-health and protective effects of exercise mediated by the secretion of exerkines. Whether these effects are observed in response to acute or chronic physical activity is still under debate. A comprehensive understanding of organ crosstalk related to exercise will help to formulate specific preventive or therapeutic plans.
This Research Topic will bring together recent work exploring the role of exerkines in interorgan crosstalk triggered by acute or chronic exercises. We welcome both original papers and up-to-date reviews and mini reviews that cover but are not limited to the following topics:
• whether regular physical activity alters the concentration of circulating exerkines associated with cardiovascular disease, type 2 diabetes mellitus, or obesity
• physiological role of circulating exerkines in the adaptation to exercise and their beneficial effect on whole-body homeostasis
• defining the FITT (frequency, intensity, time, and type) paradigm and the molecular mechanisms of exercise training in exerkines regulation
Keywords: Physical activity, cytokines, myokines, organokines, miRNA, exosomes
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.