About this Research Topic
Animal RNA viruses are well known to mutate most rapidly at the highest frequency in response to environmental pressures. RNA viruses are widely present, and more species than those of DNA viruses have been identified to exist. These RNA viruses can form the large mutated virus pools consisting of viruses with altered biological characteristics, such as infectivity, replication speed, cellular tropism, host tropism, sensitivity to anti-viral reagents, transmissibility, and/or pathogenicity. Typical examples are the above described emerging/re-emerging viruses, causative agents of AIDS, influenza, gastroenteritis, hemorrhagic fever, respiratory disorder, or etc. We must act against these pathogenic viruses on the basis of scientific evidences, i.e., fundamental information at various levels on viruses. From a medical point of view, new vaccine and drug strategies based on their highly mutable nature are required. Predicting virus mutation and evolution would be one of the key factors for future curative/preventive medicine against viral diseases.
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