Frontiers | Pharmacometabolomics and precision medicine: new insights into complex disease and drug response

Pharmacometabolomics and precision medicine: new insights into complex disease and drug response

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ORIGINAL RESEARCH

Published on 02 Dec 2016

Pharmacogenomic Study Reveals New Variants of Drug Metabolizing Enzyme and Transporter Genes Associated with Steady-State Plasma Concentrations of Risperidone and 9-Hydroxyrisperidone in Thai Autism Spectrum Disorder Patients

Sadeep Medhasi
Darawan Pinthong
Ekawat Pasomsub
Natchaya Vanwong
Nattawat Ngamsamut
Apichaya Puangpetch
Monpat Chamnanphon
Yaowaluck Hongkaew
Jirawat Pratoomwun
1 more
Chonlaphat Sukasem

Pharmacogenomic Study Reveals New Variants of Drug Metabolizing Enzyme and Transporter Genes Associated with Steady-State Plasma Concentrations of Risperidone and 9-Hydroxyrisperidone in Thai Autism Spectrum Disorder Patients

doi 10.3389/fphar.2016.00475

3,815 views
18 citations

PERSPECTIVE

Published on 27 Oct 2016

Pharmacometabolomics Informs Viromics toward Precision Medicine

Angeliki Balasopoulou
George P. Patrinos
Theodora Katsila

Pharmacometabolomics Informs Viromics toward Precision Medicine

doi 10.3389/fphar.2016.00411

2,784 views
15 citations

REVIEW

Published on 08 Sep 2016

From Metabonomics to Pharmacometabonomics: The Role of Metabolic Profiling in Personalized Medicine

Jeremy R. Everett

From Metabonomics to Pharmacometabonomics: The Role of Metabolic Profiling in Personalized Medicine

doi 10.3389/fphar.2016.00297

8,196 views
52 citations

ORIGINAL RESEARCH

Published on 14 Jun 2016

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans

Daniel M. Rotroff
Noffisat O. Oki
Xiaomin Liang
Sook Wah Yee
Sophie L. Stocker
Daniel G. Corum
Michele Meisner
Oliver Fiehn
Alison A. Motsinger-Reif
1 more
Rima Kaddurah-Daouk

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans

doi 10.3389/fphar.2016.00135

5,583 views
35 citations

ORIGINAL RESEARCH

Published on 25 Apr 2016

Functional Characterization of Human CYP2C9 Allelic Variants in COS-7 Cells

Huihui Du
Zhiyun Wei
Yucai Yan
Yuyu Xiong
Xiaoqing Zhang
Lu Shen
Yunfeng Ruan
Xi Wu
Qingqing Xu
1 more
Shengying Qin

Functional Characterization of Human CYP2C9 Allelic Variants in COS-7 Cells

doi 10.3389/fphar.2016.00098

3,377 views
9 citations

ORIGINAL RESEARCH

Published on 31 Mar 2016

Untargeted Metabolomics Reveals Dose-Response Characteristics for Effect of Rhubarb in a Rat Model of Cholestasis

Cong-En Zhang
Ming Niu
Rui-Yu Li
Wu-Wen Feng
Xiao Ma
Qin Dong
Zhi-Jie Ma
Guang-Quan Li
Ya-Kun Meng
8 more
Xiao-He Xiao

Untargeted Metabolomics Reveals Dose-Response Characteristics for Effect of Rhubarb in a Rat Model of Cholestasis

doi 10.3389/fphar.2016.00085

5,026 views
31 citations

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