About this Research Topic
Research in this area spans extensively across multiple disciplines, from establishing new, biorelevant models for the assessment of cell adhesion and migration, to developing cutting-edge software that allow us to analyze these biological pathways and into understanding complex cellular events in an in vivo setting. The goal of this research topic is to amalgamate these research areas and to better equip research groups throughout the entire workflow process. Through the streamlining of standard protocols, the ideology of addressing unanswered questions and reaching optimum outcomes in cell adhesion and migration, whether that be in the production of tissue mimics for implantation or for drug-disease modelling for instance, becomes more attainable.
The scope of this research topic aims to cover the topics over the whole of the cell adhesion and migration analysis workflow, including (but not limited to):
• Cytoskeleton arrangement
• Knockdown models
• Cell mechanobiology
• Extracellular matrix interactions and stiffness
• Production of biorelevant models
• Biomaterials
• 3D Bioprinting and culture
• Cell labelling
• Cell processing assays
• Advanced imaging technologies
• Novel software analysis packages
We are particularly interested in the following article types:
• Methods: Describing either new or existing methods that are significantly improved or adapted for specific purposes. These manuscripts may include primary (original) data. Novelty may vary, but the utility of a method or protocol must be evident
• Original Research presenting new findings in the use of iPSCs in ophthalmological research.
• Reviews and mini-reviews on recent advances and topical methods and protocols highlighting the important future directions of the field.
• Technology and Code articles providing novel insights or approaches.
• Perspectives and Opinions on methods, protocols and advances relevant for cell adhesion and migration research.
Keywords: Cell adhesion, Cell migration, Workflows, Models
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.