About this Research Topic
Central and peripheral nervous system diseases, such as stroke, altitude hypoxia brain injury, perinatal and neonatal brain hypoxia, Alzheimer's disease, epilepsy, sciatica, etc., involve complex molecular regulatory mechanisms, and seriously threaten people's life safety. Multiple omics techniques, such as genomics, transcriptomics, proteomics, metabolomics, or the emerging single-cell, and spatio-temporal transcriptomics, or mitochondrial omics, provide powerful tools for uncovering complex networks of disease pathogenesis and screening key potential targets for drug therapy. In order to better understand the pathogenesis and treatment of the above diseases in nervous system Frontiers in Genetics launches this research topic, aiming to indicate the future research direction of nervous system by combining multiple omics techniques.
1. The advanced emerging omics techniques such as single-cell and spatio-temporal transcriptomics, or their combined applications, for the investigation of the above nervous system diseases.
2. The combination of omics technology and bioinformatics to analyze the pathogenesis and potential therapeutic drugs of nervous system diseases.
3. Natural or synthetic compounds with potential in the treatment of nervous system diseases and their key molecular mechanisms.
4. The application potential of omics technology in clinical diagnosis, pathogenesis and new drug development of nervous system diseases.
5. The development status, limitations and future direction of omics technology on nervous system diseases.
The purpose of this topic is to focus on the contribution of researchers worldwide on the potential application of omics techniques in nervous system diseases. We accept any articles on the application of conventional genomics, transcriptomics, proteomics, metabolomics, or the emerging single-cell, and spatio-temporal transcriptomics, or mitochondrial omics to the exploration of mechanisms and drugs (herbal compound prescriptions, herbal medicines, and natural or synthetic compounds) for nervous system diseases. We seek to advance the clinical diagnosis, pathogenesis and drug development of nervous system diseases with the help of multiomics technologies. Our articles cover, but are not limited to, original basic and clinical research papers, review papers, mini-reviews, meta-analyses, etc.
1. The advanced emerging omics techniques such as single-cell and spatio-temporal transcriptomics, or their combined applications, for the investigation of the above nervous system diseases.
2. The combination of omics technology and bioinformatics to analyze the pathogenesis and potential therapeutic drugs of nervous system diseases.
3. Natural or synthetic compounds with potential in the treatment of nervous system diseases and their key molecular mechanisms.
4. The application potential of omics technology in clinical diagnosis, pathogenesis and new drug development of nervous system diseases.
5. The development status, limitations and future direction of omics technology on nervous system diseases.
The purpose of this topic is to focus on the contribution of researchers worldwide on the potential application of omics techniques in nervous system diseases. We accept any articles on the application of conventional genomics, transcriptomics, proteomics, metabolomics, or the emerging single-cell, and spatio-temporal transcriptomics, or mitochondrial omics to the exploration of mechanisms and drugs (herbal compound prescriptions, herbal medicines, and natural or synthetic compounds) for nervous system diseases. We seek to advance the clinical diagnosis, pathogenesis and drug development of nervous system diseases with the help of multiomics technologies. Our articles cover, but are not limited to, original basic and clinical research papers, review papers, mini-reviews, meta-analyses, etc.
Keywords: Multiomics, Nervous System
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
