About this Research Topic
Globally, cancer is one of the leading causes of death; as per the World Health Organization (WHO). In 2020, nearly 10 million deaths were reported due to cancer. The most commonly reported cancers include those of the breast, brain, lung, colon, rectum, and prostate. In most cases, delayed diagnosis and staging of cancer lead to the delayed intervention of therapy. Treating cancer in the benign stage is easy, but when it spreads to distal parts of the body in the malignant stage, treatment becomes more difficult. Detecting cancer at its early stage is the key point in controlling and treating the disease. Currently, available cancer therapies include surgery, chemotherapy, radiotherapy, photothermal therapy, and immunotherapy. All of these treatments can involve the recurrence of cancer and severe side effects.
Severe toxicity can appear in the vital organs (lungs, liver, and kidney) as a result of higher doses and off-target delivery of chemotherapeutic agents. A targeted drug delivery system (TDDS) is a therapeutic delivery platform that releases the drug at a preselected biosite in a controlled manner. As the drug will be delivered to the targeted site, the dose required to produce a therapeutic effect will be lesser than the conventional dose and toxicity to the vital organs can be avoided. Additionally, nanotechnology-based delivery systems are making a significant impact on cancer treatment and polymers play a key role in the development of nanoparticulate carriers for cancer therapy. A drug delivery system integrated with a diagnostic and therapeutic agent would be capable of diagnosing the disease and producing therapeutic effects simultaneously. Additionally, the real-time therapeutic efficacy of the treatment can be monitored.
For this Research Topic, we welcome Original Research Articles, Reviews, and Mini-reviews that focus on the following topics:
• Formulation and evaluation of drug delivery system for cancer therapy
• Surface modified drug delivery system for cancer therapy.
• Targeted nanomedicine for cancer imaging and therapy.
• Advanced nanomaterials for cancer diagnosis/imaging
• Targeted ligand functionalized nanomaterial for cancer therapy.
• Development and in-vitro/in-vivo characterization of multifunctional nanomedicine for cancer diagnosis and therapy.
• Theranostic nanomedicine for targeted cancer imaging and therapy.
Severe toxicity can appear in the vital organs (lungs, liver, and kidney) as a result of higher doses and off-target delivery of chemotherapeutic agents. A targeted drug delivery system (TDDS) is a therapeutic delivery platform that releases the drug at a preselected biosite in a controlled manner. As the drug will be delivered to the targeted site, the dose required to produce a therapeutic effect will be lesser than the conventional dose and toxicity to the vital organs can be avoided. Additionally, nanotechnology-based delivery systems are making a significant impact on cancer treatment and polymers play a key role in the development of nanoparticulate carriers for cancer therapy. A drug delivery system integrated with a diagnostic and therapeutic agent would be capable of diagnosing the disease and producing therapeutic effects simultaneously. Additionally, the real-time therapeutic efficacy of the treatment can be monitored.
For this Research Topic, we welcome Original Research Articles, Reviews, and Mini-reviews that focus on the following topics:
• Formulation and evaluation of drug delivery system for cancer therapy
• Surface modified drug delivery system for cancer therapy.
• Targeted nanomedicine for cancer imaging and therapy.
• Advanced nanomaterials for cancer diagnosis/imaging
• Targeted ligand functionalized nanomaterial for cancer therapy.
• Development and in-vitro/in-vivo characterization of multifunctional nanomedicine for cancer diagnosis and therapy.
• Theranostic nanomedicine for targeted cancer imaging and therapy.
Keywords: Cancer imaging, Cancer therapy, Targeted nanomedicine, Theranostic nanomedicine, multifunctional nanoparticles, drug delivery
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
