About this Research Topic
The recent development of new gene targeting related tools (e.g. base editors, prime editing, GRAND, pfAGO, SHERLOCK, DETECTR, PAC-MAN, ABACAS, etc.) and the identification of novel regulators in virus lifecycles brings us the opportunity to combat viral diseases by using genome editing of both viral or host targets. In addition, the emerging and re-emerging viruses continue to threaten humans and animals. However, we don't have enough methods to treat viral diseases yet. Gene targeting shows a promising prospect in the prevention of viral diseases in the future.
The goal of this Research Topic is to cover recent advances in the prevention of viral diseases by gene targeting - specifically for the serious viral diseases caused by Human Immunodeficiency Virus (HIV), Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), SARS-CoV-2, Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Papillomavirus (HPV), Epstein–Barr Virus (EBV), Zika Virus (ZIKV), Dengue Virus (DENV), West Nile Virus (WNV), Influenza Virus, Ebola Virus (EBOV) etc. We would like to bring the significant progresses in gene editing or modification of classic or novel host factors that are involved in the life cycle of these viruses to the attention of the scientific community. In addition, the promising and emerging methods for the detection of viral infections are also needed in combating viral diseases.
We welcome research articles, review articles, letters and short communications that cover the following areas, but are not limited to:
• New detection tools in viral infection
• Novel methods in viral genome editing, including RNA and DNA viruses
• Disruption of viral genes by gene editing
• Gene targeting or modification of host factors in the prevention of viral diseases
The goal of this Research Topic is to cover recent advances in the prevention of viral diseases by gene targeting - specifically for the serious viral diseases caused by Human Immunodeficiency Virus (HIV), Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), SARS-CoV-2, Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Papillomavirus (HPV), Epstein–Barr Virus (EBV), Zika Virus (ZIKV), Dengue Virus (DENV), West Nile Virus (WNV), Influenza Virus, Ebola Virus (EBOV) etc. We would like to bring the significant progresses in gene editing or modification of classic or novel host factors that are involved in the life cycle of these viruses to the attention of the scientific community. In addition, the promising and emerging methods for the detection of viral infections are also needed in combating viral diseases.
We welcome research articles, review articles, letters and short communications that cover the following areas, but are not limited to:
• New detection tools in viral infection
• Novel methods in viral genome editing, including RNA and DNA viruses
• Disruption of viral genes by gene editing
• Gene targeting or modification of host factors in the prevention of viral diseases
Keywords: Viral diseases, gene editing, gene targeting, viral gene, host factor
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
