About this Research Topic
World Health Organisation (WHO) has provided a set of detailed guidelines for measuring disease burden at the local or national level. WHO also introduced the disability-adjusted life years (DALY) as a new metric to quantify the burden of diseases, injuries and risk factors. Although many of these diseases has treatment, however sometimes it cannot be effective. The loss of effectiveness frequently is related to the drug insolubility in water or body fluids, drug degradation by environmental or biological factors, no absorption or non-regular pharmacokinetics related to the patient.
To overcome the barrier to therapeutics, the research and development of nanomaterials and biomaterials have been exploited for the controlled release of drugs related to time and spatial release. Several materials have been exploited and they are designed by metals, polymers, proteins, lipids or composites each with exceptional proprieties to biological purposes. Based on these aspects, the encapsulation of new drugs can be encapsulated against diseases that are highly needed or withdrawn drugs because of risks to patients could be reintroduced in the market.
Recently, the uses of nano- and biomaterials for the diagnosis of diseases is growing, applications of such materials must be considered for use in:
• clinical analysis
• biosensors
• diagnostic imaging - particularly of malignant tumor cells
• detection of molecular markers in some diseases (such as enzymes, antibodies, ligand molecules or released chemical mediators).
Nanotechnology-based sensors offer a more sensitive response, and more versatile detection mechanism, as well as providing ultralow limits of detection.
In this Research Topic, we invite experts on Nano- and Biomaterials to share their knowledge with the scientific community. This requires the coordinated effort of multiple disciplines such as:
• Pharmaceuticals
• Materials Engineering
• Chemistry
• Pharmacology
• Microbiology
• Immunology
and other correlated disciplines.
Keywords: nanomaterials, biomaterials, nanoscience, malignant tumours, infectious diseases, pharmaceutical design, nanoscale
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.