Around 80% of animal diseases are viral infections, and many of these pose serious threats to the health of humans, farmed livestock and wild animals alike. Mammalian viruses particularly can have huge impacts on public health and the economy, as demonstrated by outbreaks of foot-and-mouth disease (FMDV), Japanese Encephalitis Virus (JEV) and African Swine Fever Virus (ASFV) in recent decades. Moreover, radical changes in farming practices and livestock transportation have greatly increased the difficulty in controlling and preventing the spread of these viral diseases. In recent years, the outbreak and spread of human emerging infectious diseases caused by the viruses that originate in animals, such as MERS-CoV, ZIKV, SARS-CoV and SARS-CoV-2, have highlighted the dire need for specific antiviral drugs and vaccines to tackle these viruses of mammalian origin. Therefore, research on molecular mechanisms underlying viral infection and pathogenesis, and the development of effective antiviral drugs and vaccines that can be scaled up for scale production, is of pivotal importance.
Mammalian viruses result in great economic losses worldwide and have caused the majority of recent pandemics in human populations, yet for many of these viruses there are currently no specific drugs and new viral mutations mean that existing vaccines are failing. Furthermore, we are still far away from fully understanding the genetic variations, epidemiology, infection and pathogenic mechanisms of these viruses. In this Research Topic, we focus on important mammalian viruses, especially the viruses among livestock that might cause global pandemics or even threaten well-being in humans. We would like to explore new insights that will guide us to improve the prevention and control strategies of animal viral diseases.
The editors encouraged the submission of Original Research, Reviews, Mini-Reviews, Method papers, and others in the following (but not limited to) topics:
- Viral genetics, molecular epidemiology and risk assessment
- Virus evolution and ecology
- Viral infection and immunologic response
- Viral pathogenesis and host-viral interactions
- New diagnostic agents and vaccine development
Around 80% of animal diseases are viral infections, and many of these pose serious threats to the health of humans, farmed livestock and wild animals alike. Mammalian viruses particularly can have huge impacts on public health and the economy, as demonstrated by outbreaks of foot-and-mouth disease (FMDV), Japanese Encephalitis Virus (JEV) and African Swine Fever Virus (ASFV) in recent decades. Moreover, radical changes in farming practices and livestock transportation have greatly increased the difficulty in controlling and preventing the spread of these viral diseases. In recent years, the outbreak and spread of human emerging infectious diseases caused by the viruses that originate in animals, such as MERS-CoV, ZIKV, SARS-CoV and SARS-CoV-2, have highlighted the dire need for specific antiviral drugs and vaccines to tackle these viruses of mammalian origin. Therefore, research on molecular mechanisms underlying viral infection and pathogenesis, and the development of effective antiviral drugs and vaccines that can be scaled up for scale production, is of pivotal importance.
Mammalian viruses result in great economic losses worldwide and have caused the majority of recent pandemics in human populations, yet for many of these viruses there are currently no specific drugs and new viral mutations mean that existing vaccines are failing. Furthermore, we are still far away from fully understanding the genetic variations, epidemiology, infection and pathogenic mechanisms of these viruses. In this Research Topic, we focus on important mammalian viruses, especially the viruses among livestock that might cause global pandemics or even threaten well-being in humans. We would like to explore new insights that will guide us to improve the prevention and control strategies of animal viral diseases.
The editors encouraged the submission of Original Research, Reviews, Mini-Reviews, Method papers, and others in the following (but not limited to) topics:
- Viral genetics, molecular epidemiology and risk assessment
- Virus evolution and ecology
- Viral infection and immunologic response
- Viral pathogenesis and host-viral interactions
- New diagnostic agents and vaccine development