About this Research Topic
Metabolic syndrome is characterized as a collection of endocrine and inflammatory based pathological conditions including obesity, hyperglycemia, hypertension, and insulin resistance. The prevalence of metabolic-associated diseases resulting in gynecological problems has risen globally in recent decades. Women’s reproductive health is impacted through disruption of hormonal regulation, ovarian function, fertilization, and pregnancy establishment. These physiological alterations may increase the risk of ectopic pregnancies, pelvic inflammatory disease, anovulation, menorrhagia and other menstrual disorders, miscarriage, recurrent pregnancy loss (RPL), gestational diabetes (GDM), preterm birth, to name a few. There is therefore an urgent need to develop and implement more effective and efficient therapeutic interventions for these gynecological disorders through evidence-based, patient-centered care.
The aim of this Research Topic is to determine research studies focused on metabolic alterations that affect female reproductive health, and to explore novel and effective therapeutic interventions. Metabolic disorders are heterogeneous and their effects on female reproductive health are immense. Hence, characterizing these effects in order to develop intentional research of targeted and refined therapeutic interventions is critical to improving women’s health.
We are interested in ongoing basic, translational and applied research that characterize the varied metabolic alterations associated with metabolic syndrome that directly or indirectly may affect long-term women’s reproductive health.
Potential topics may include, but are not limited to:
Metabolic alterations affecting ovulation, uterine physiology, fertilization, and pregnancy.
Hormonal dysregulations due to metabolic alterations.
Investigation of therapeutic targets for metabolic alteration associated with infertility.
Cardiovascular risk and PCOS interaction across the reproductive lifespan of women.
Metabolic syndrome as a risk factor for pregnancy complications such as preeclampsia and gestational diabetes.
Topic Coordinator Manasi Kamat is employed by Amazon and holds shares in Amazon, Netflix, Intel, Meta, Vroom, 10x Genomics, Google, Apple, Microsoft, and Lemonade. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
The aim of this Research Topic is to determine research studies focused on metabolic alterations that affect female reproductive health, and to explore novel and effective therapeutic interventions. Metabolic disorders are heterogeneous and their effects on female reproductive health are immense. Hence, characterizing these effects in order to develop intentional research of targeted and refined therapeutic interventions is critical to improving women’s health.
We are interested in ongoing basic, translational and applied research that characterize the varied metabolic alterations associated with metabolic syndrome that directly or indirectly may affect long-term women’s reproductive health.
Potential topics may include, but are not limited to:
Metabolic alterations affecting ovulation, uterine physiology, fertilization, and pregnancy.
Hormonal dysregulations due to metabolic alterations.
Investigation of therapeutic targets for metabolic alteration associated with infertility.
Cardiovascular risk and PCOS interaction across the reproductive lifespan of women.
Metabolic syndrome as a risk factor for pregnancy complications such as preeclampsia and gestational diabetes.
Topic Coordinator Manasi Kamat is employed by Amazon and holds shares in Amazon, Netflix, Intel, Meta, Vroom, 10x Genomics, Google, Apple, Microsoft, and Lemonade. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Keywords: Lifestyle factors, Metabolic disorder, Hormone dysregulation, Infertility, Embryo implantation
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
