It has been well established that the combination of exercise with hypoxia induces some physiological responses and specific adaptations, not observed to a similar extent when performing the same exercise in normoxia. Traditionally, hypoxic conditioning has been used by athletes for performance improvement, but appears also relevant for health enhancement in different pathological populations. For instance, sarcopenia, bone remodeling, chronic inflammation, among others benefit from hypoxic conditioning-related intervention. However, the results reported are not unanimous regarding the physiological responses, with some confounding factors - hypoxic mode (hypobaric hypoxia vs. normobaric hypoxia) and severity (fraction of inspired oxygen) or training load (volume, intensity, exercise ratio and/or recovery) - being susceptible to influence the expected changes to a greater or lesser extent.
This research topic therefore aims to present original experimental findings that may participate to clarify the different underlying mechanisms in relation to both environmental- and/or training-induced factors. A particular focus on the kinetics of physiological responses, short-, mid- and long-term adaptation of the various pathways (e.g., vascular, molecular) will be highly appreciated to appraise their effect on exercise performance, health and well-being of healthy participants (along the continuum of sport practice levels), patients presenting comorbidities (e.g., obesity, hypertension, diabetes) and elderly. Reporting the interindividual variability when using the available hypoxic conditioning methods (e.g. resistance training in hypoxia, repeated-sprint training in hypoxia) would be also really valuable in the understanding of the adaptation process as well as for practical application/guidance.
This special issue will cover the following themes: Environmental Physiology, exercise physiology, cardiovascular/respiratory physiology, integrative physiology, redox physiology, molecular biology and therapeutics, autonomic neuroscience, neurophysiology/neuromechanics, cognition, well-being. Original research, mini-reviews, reviews and systematic reviews, as well as perspectives will be preferably considered, but not limited to.
It has been well established that the combination of exercise with hypoxia induces some physiological responses and specific adaptations, not observed to a similar extent when performing the same exercise in normoxia. Traditionally, hypoxic conditioning has been used by athletes for performance improvement, but appears also relevant for health enhancement in different pathological populations. For instance, sarcopenia, bone remodeling, chronic inflammation, among others benefit from hypoxic conditioning-related intervention. However, the results reported are not unanimous regarding the physiological responses, with some confounding factors - hypoxic mode (hypobaric hypoxia vs. normobaric hypoxia) and severity (fraction of inspired oxygen) or training load (volume, intensity, exercise ratio and/or recovery) - being susceptible to influence the expected changes to a greater or lesser extent.
This research topic therefore aims to present original experimental findings that may participate to clarify the different underlying mechanisms in relation to both environmental- and/or training-induced factors. A particular focus on the kinetics of physiological responses, short-, mid- and long-term adaptation of the various pathways (e.g., vascular, molecular) will be highly appreciated to appraise their effect on exercise performance, health and well-being of healthy participants (along the continuum of sport practice levels), patients presenting comorbidities (e.g., obesity, hypertension, diabetes) and elderly. Reporting the interindividual variability when using the available hypoxic conditioning methods (e.g. resistance training in hypoxia, repeated-sprint training in hypoxia) would be also really valuable in the understanding of the adaptation process as well as for practical application/guidance.
This special issue will cover the following themes: Environmental Physiology, exercise physiology, cardiovascular/respiratory physiology, integrative physiology, redox physiology, molecular biology and therapeutics, autonomic neuroscience, neurophysiology/neuromechanics, cognition, well-being. Original research, mini-reviews, reviews and systematic reviews, as well as perspectives will be preferably considered, but not limited to.