About this Research Topic
The mitral valve is the left-sided atrioventricular valve in the human heart, that maintains unidirectional blood flow from the left atrium to the left ventricle. Mitral stenosis (MS) and mitral regurgitation (MR) are two lesions of the valve that disrupt this blood flow and are caused due to a variety of etiologies.
This Research Topic invites submissions focused on mitral valve disease mechanisms and new therapies. Disease mechanistic studies may be genetic, biological, biomechanical or mechanobiological, and should provide new insights into mitral valve diseases of any etiology. Both experimental and computational approaches are welcome if they elucidate the mechanistic basis of any form of mitral valve disease.
New therapies can be pharmacological, surgical or interventional, either in the pre-clinical stage or early clinical stages. Submissions may be from any model system, such as in vitro studies, in vivo acute or chronic animal studies, or extending into human studies as well.
This Research Topic invites submissions focused on mitral valve disease mechanisms and new therapies. Disease mechanistic studies may be genetic, biological, biomechanical or mechanobiological, and should provide new insights into mitral valve diseases of any etiology. Both experimental and computational approaches are welcome if they elucidate the mechanistic basis of any form of mitral valve disease.
New therapies can be pharmacological, surgical or interventional, either in the pre-clinical stage or early clinical stages. Submissions may be from any model system, such as in vitro studies, in vivo acute or chronic animal studies, or extending into human studies as well.
Keywords: Mitral Valve Disease, disease mechanisms, therapeutic targets, computational modeling, experimental modeling, animal studies
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
