Pathogenic and Symbiotic Bacteria in Ruminants: Antimicrobial Resistance and Microbial Homeostasis

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About this Research Topic

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Background

Ruminants have been domesticated for thousands of years, living alongside and providing many benefits to human beings in various ways. They provide food, fiber, power, biomaterials, and share in providing traditional medicine for people worldwide. However, bacterial infections do not only impact domestic and wild animals which may cause economic loss and health issues but also represent a great threat to the health of human beings. Moreover, due to the inadvertent use of antimicrobials, especially in the treatment of bovine mastitis, the resultant antimicrobial resistance is raising our concerns. Meanwhile, symbiotic bacteria play an important role in the ruminants who have a unique digestive system that allows them to better use energy from fibrous plant material than other herbivores. Therefore, all of these challenges urge researchers to pay more attention to the emergence and the molecular characterization of pathogenic/multidrug-resistant bacteria in addition to the gastroenterological microbiome dysbiosis in ruminants.

The purpose of this Research Topic is to highlight and stimulate discussions regarding the antimicrobial resistance and microbial homeostasis of pathogenic and symbiotic bacteria in ruminants and their products, thereby helping us further understand the role of bacteria in the pathological and physiological processes of ruminants. In addition, more attention should be paid to low-cost and effective antimicrobials alternatives for the prevention and/or treatment of bacterial diseases in ruminants, in order to reduce the potential threat to the health of human beings resulting from the overreliance on antimicrobial therapy.

We enthusiastically welcome researchers/colleagues to submit their valuable reports to Frontiers in Veterinary Science, in the forms of Original Research, Review, Mini Review, Brief Research Report, and Perspective. Suitable subtopics for this Research Topic are included and listed below, but not limited to:

• The molecular mechanisms and/or serological studies of the infectious diseases caused by Escherichia, Salmonella, Pseudomonas, Klebsiella, Mycobacterium, and Brucella in cattle, sheep, goats, buffaloes, camels, deer, and wild ruminants.

• The molecular characterization and phylogenetic analyses of pathogenic and/or symbiotic bacteria recovered from ruminants or their products.

• The emergence, prevalence, and/or incidence of multidrug-resistant bacteria in ruminants.

• Phenotypic and genotypic characterization of resistant bacteria isolated from ruminants.

• Antimicrobials alternatives for the prevention and/or treatment of veterinary infectious diseases in ruminants.

• Intestinal and rumen microbial homeostasis/dysbiosis in ruminants.

• Microbiome metagenomic sequencing analysis of intestinal, rumen, and raw milk samples of ruminants.

Keywords: ruminant, pathogenic bacteria, symbiotic bacteria, antimicrobial resistance, microbial homeostasis, microbiome, dysbiosis

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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