Frontiers | Evolutionary Biology of Tumor Initiation and Progression

Evolutionary Biology of Tumor Initiation and Progression

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ORIGINAL RESEARCH

Published on 08 Feb 2024

Inhibition of OCT4 binding at the MYCN locus induces neuroblastoma cell death accompanied by downregulation of transcripts with high-open reading frame dominance

Kazuma Nakatani
Hiroyuki Kogashi
Takanori Miyamoto
Taiki Setoguchi
Tetsushi Sakuma
Kazuto Kugou
Yoshinori Hasegawa
Takashi Yamamoto
Yoshitaka Hippo
Yusuke Suenaga

doi 10.3389/fonc.2024.1237378

1,695 views
1 citation

REVIEW

Published on 19 Dec 2023

Multiomics insights on the onset, progression, and metastatic evolution of breast cancer

Lucia Alvarez-Frutos
Daniel Barriuso
Mercedes Duran
Mar Infante
Guido Kroemer
Roberto Palacios-Ramirez
Laura Senovilla

doi 10.3389/fonc.2023.1292046

3,027 views
3 citations

REVIEW

Published on 07 Dec 2023

Hemangiosarcoma in dogs as a potential non-rodent animal model for drug discovery research of angiosarcoma in humans

Kazuki Heishima
Naohiko Aketa
Mizuki Heishima
Asuka Kawachi

doi 10.3389/fonc.2023.1250766

2,564 views
2 citations

ORIGINAL RESEARCH

Published on 23 Nov 2023

Structural characterization of human de novo protein NCYM and its complex with a newly identified DNA aptamer using atomic force microscopy and small-angle X-ray scattering

Seigi Yamamoto
Fumiaki Kono
Kazuma Nakatani
Miwako Hirose
Katsunori Horii
Yoshitaka Hippo
Taro Tamada
Yusuke Suenaga
Tatsuhito Matsuo

doi 10.3389/fonc.2023.1213678

2,525 views
6 citations

HYPOTHESIS AND THEORY

Published on 09 Nov 2023

The permissive binding theory of cancer

Caroline M. Weisman

doi 10.3389/fonc.2023.1272981

1,701 views

REVIEW

Published on 07 Nov 2023

Evolutionary reversion in tumorigenesis

Yosuke Nagahata
Hiroshi Kawamoto

doi 10.3389/fonc.2023.1282417

1,125 views
2 citations

ORIGINAL RESEARCH

Published on 28 Sep 2023

Mathematical analysis identifies the optimal treatment strategy for epidermal growth factor receptor-mutated non-small cell lung cancer

Qian Yu
Susumu S. Kobayashi
Hiroshi Haeno

doi 10.3389/fonc.2023.1137966

1,741 views

ORIGINAL RESEARCH

Published on 27 Jan 2023

mTOR pathway as a potential therapeutic target for cancer stem cells in canine mammary carcinoma

Masaki Michishita
Kazuhiko Ochiai
Rei Nakahira
Daigo Azakami
Yukino Machida
Tomokazu Nagashima
Takayuki Nakagawa
Toshiyuki Ishiwata

doi 10.3389/fonc.2023.1100602

2,377 views
7 citations

CASE REPORT

Published on 11 Jan 2023

Unusual phylogenetic tree and circulating actionable ESR1 mutations in an aggressive luminal/HER2-low breast cancer: Case report

Matteo Allegretti
Vittoria Barberi
Cristiana Ercolani
Antonello Vidiri
Elena Giordani
Gennaro Ciliberto
Patrizio Giacomini
Alessandra Fabi

doi 10.3389/fonc.2022.1050452

1,492 views
1 citation

REVIEW

Published on 08 Aug 2022

Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles

Gábor Valcz
Beáta Újvári
Edit I. Buzás
Tibor Krenács
Sándor Spisák
Ágnes Kittel
Zsolt Tulassay
Péter Igaz
István Takács
Béla Molnár

doi 10.3389/fonc.2022.945376

3,944 views
21 citations

BRIEF RESEARCH REPORT

Published on 19 Jul 2022

The Role of Clonal Evolution on Progression, Blood Parameters, and Response to Therapy in Multiple Myeloma

Sarah Sandmann
Katharina Karsch
Peter Bartel
Rita Exeler
Tobias J. Brix
Elias K. Mai
Julian Varghese
Georg Lenz
Cyrus Khandanpour

doi 10.3389/fonc.2022.919278

1,734 views
5 citations

BRIEF RESEARCH REPORT

Published on 08 Jul 2022

Clonal Evolution at First Sight: A Combined Visualization of Diverse Diagnostic Methods Improves Understanding of Leukemic Progression

Sarah Sandmann
Yvonne Lisa Behrens
Claudia Davenport
Felicitas Thol
Michael Heuser
Daniela Dörfel
Friederike Löhr
Agnes Castrup
Doris Steinemann
3 more
Gudrun Göhring

doi 10.3389/fonc.2022.888114

1,871 views
2 citations

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Articles

Inhibition of OCT4 binding at the MYCN locus induces neuroblastoma cell death accompanied by downregulation of transcripts with high-open reading frame dominance

Multiomics insights on the onset, progression, and metastatic evolution of breast cancer

Hemangiosarcoma in dogs as a potential non-rodent animal model for drug discovery research of angiosarcoma in humans

Structural characterization of human de novo protein NCYM and its complex with a newly identified DNA aptamer using atomic force microscopy and small-angle X-ray scattering

The permissive binding theory of cancer

Evolutionary reversion in tumorigenesis

Mathematical analysis identifies the optimal treatment strategy for epidermal growth factor receptor-mutated non-small cell lung cancer

mTOR pathway as a potential therapeutic target for cancer stem cells in canine mammary carcinoma

Unusual phylogenetic tree and circulating actionable ESR1 mutations in an aggressive luminal/HER2-low breast cancer: Case report

Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles

The Role of Clonal Evolution on Progression, Blood Parameters, and Response to Therapy in Multiple Myeloma

Clonal Evolution at First Sight: A Combined Visualization of Diverse Diagnostic Methods Improves Understanding of Leukemic Progression

Frontiers in Oncology

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