Mapping enzyme activity: From novel diagnostics to target-based therapeutics, how activity-based probes are improving our understanding of biological catalysts

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EDITORIAL

Published on 22 Aug 2023

Editorial: Mapping enzyme activity: from novel diagnostics to target-based therapeutics, how activity-based probes are improving our understanding of biological catalysts

André Luiz Lourenço

doi 10.3389/fphar.2023.1271247

876 views
2 citations

ORIGINAL RESEARCH

Published on 26 Jan 2023

Characterizing metabolic drivers of Clostridioides difficile infection with activity-based hydrazine probes

Katelyn A. Bustin
Arwa Abbas
Xie Wang
Michael C. Abt
Joseph P. Zackular
Megan L. Matthews

doi 10.3389/fphar.2023.1074619

3,570 views
4 citations

ORIGINAL RESEARCH

Published on 29 Aug 2022

Discovering monoacylglycerol lipase inhibitors by a combination of fluorogenic substrate assay and activity-based protein profiling

Hui Deng
Qianwen Zhang
Qian Lei
Na Yang
Kai Yang
Jianbing Jiang
Zhiyi Yu

doi 10.3389/fphar.2022.941522

2,457 views
5 citations

REVIEW

Published on 09 Jul 2021

Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease

Maria I. Avrutsky
Carol M. Troy

doi 10.3389/fphar.2021.701301

16,317 views
100 citations

ORIGINAL RESEARCH

Published on 24 Sep 2020

Comparison of CYP2C9 Activity in Ethiopian and Non-Ethiopian Jews Using Phenytoin as a Probe

Zahi Abu Ghosh
Shoshana Alamia
Chanan Shaul
Yoseph Caraco

doi 10.3389/fphar.2020.566842

2,218 views
3 citations

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Frontiers in Pharmacology

Experimental Pharmacology and Drug Discovery

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