Advances in Novel Natural Product Pesticides

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About this Research Topic

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Background

Global food safety/security will remain a worldwide concern for the next 50 years and beyond. Plant pests and diseases have had an enormous impact on food safety/security at various stages of the food chain, from primary production to consumption. Plant pests and diseases have presented serious threats in agricultural production and caused enormous economic losses each year worldwide. Although pesticide application has been the conventional methodology used in plant protection, frequent use of conventional chemical pesticides has resulted in problems in resistance in bacteria/fungi/pests populations, environmental contamination, and human health. With the improvement of human living standards and human health, the demand for high-quality agricultural products as foods makes it necessary to limit the use of conventional chemical pesticides and challenges the control of plant pests and diseases. Therefore, the current paradigm of relying almost exclusively on conventional chemical pesticides for plant pests and diseases control may need to be reconsidered.

Healthy plants and a healthy environment are important safeguards against pests and diseases of our crops, ensuring a sustainable food supply. A healthy soil–water–plant ecology will improve both productivity and the harmony between agriculture and the growing world population. Similar to a healthy microbiome that promotes human health, a healthy ecosystem will provide abundant and healthy food now and in the future. Natural product pesticides of using innate disease-resistant plants against resist pests and diseases is an innovative stratagem in sustainable agricultural development because these pesticides are safer than conventional chemical pesticides on account of their rapid environmental biodegradation and low toxicity to natural enemies, humans, and other mammals and they suffer less from problems of registration difficulties. Since prehistoric times, people in all parts of the world have exploited natural products in one form or another in curing diseases and fighting pests and diseases that endanger their health or compete for their food. Therefore, natural products can be used either directly in pest control or can serve as models for the development of novel synthetic analogs with favorable biological and physiochemical properties.

This Special Issue intends to highlight the advances in novel natural product pesticides. Manuscripts submitted should present recent advances in novel natural product pesticides and other relevant research fields.

We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:

• Research on the biomimetic synthesis of novel analogs of natural product pesticides.

• Research on the total synthesis of novel natural product pesticides.

• Research on the isolation and structure elucidation of novel natural products.

• Research on the toxicology of novel natural product pesticides.

• Research on the mechanism of action of novel natural product pesticides.

Keywords: Natural product pesticides, Biomimetic synthesis, Total synthesis, Plant pests and diseases

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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