About this Research Topic
Diabetic Retinopathy is a common complication affecting patients with diabetes and refers to microvascular retinal damage as a result of hyperglycaemia. Without intervention, damage can progress through the stages of background, pre-proliferative and proliferative retinopathy, potentialling resulting diabetic macular edema and the loss of vision. As a leading cause of visual impairment and sight loss understanding the disease is a key area of inquiry.
The early stages of retinopathy can occur without symptoms and pain. Therefore, timely diagnosis can be essential in preventing the disease progression to advances stages where influences on vision will occur. For such reasons, advances in methods of diagnosis and screening will be considered.
This collection will also seek to explore studies contributing to our understanding of the disease progression. Research into the associations between inflammatory hormones and diabetic retinopathy are of interest as well as the significance of different metabolites in early diagnosis and later stage therapeutics.
In this article collection we hope to highlight recent advances contributing to our understanding of diabetic retinopathy. We will accept both original research and reviews on the following, but not limited to, subjects:
• Screening methods to improve early detection of retinopathy
• Techniques for imaging the retinal layers
• Associations between glycemic variability and retinal neurodegeneration
• Advances in understanding of the metabolic pathways implicated in hyperglycemia-induced microvascular damage
• The association between inflammation and oxidative stress on diabetic retinopathy as well as identification of inflammatory biomarkers of endothelial dysfunction
• Studies into understanding the disease progression through omics techniques
The early stages of retinopathy can occur without symptoms and pain. Therefore, timely diagnosis can be essential in preventing the disease progression to advances stages where influences on vision will occur. For such reasons, advances in methods of diagnosis and screening will be considered.
This collection will also seek to explore studies contributing to our understanding of the disease progression. Research into the associations between inflammatory hormones and diabetic retinopathy are of interest as well as the significance of different metabolites in early diagnosis and later stage therapeutics.
In this article collection we hope to highlight recent advances contributing to our understanding of diabetic retinopathy. We will accept both original research and reviews on the following, but not limited to, subjects:
• Screening methods to improve early detection of retinopathy
• Techniques for imaging the retinal layers
• Associations between glycemic variability and retinal neurodegeneration
• Advances in understanding of the metabolic pathways implicated in hyperglycemia-induced microvascular damage
• The association between inflammation and oxidative stress on diabetic retinopathy as well as identification of inflammatory biomarkers of endothelial dysfunction
• Studies into understanding the disease progression through omics techniques
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
