About this Research Topic
The ocean spans three-quarters of the earth's surface and supplies us with important natural resources. Following advances in synthetic biology, we are now able to tap into the oceans resources as never before. Marine bacteria and microalgae, which are the dominant primary producers in marine ecosystems, are ideal hosts for synthetic biology. In recent years, the marine diatom Phaeodactylum tricornutum and the marine bacteria Vibrio natriegens, for example, have been increasingly investigated. Cell factories can manufacture a wide range of bioactive chemicals, precursors, and even novel substances by inducing external pathways and manipulating the metabolic network. The creation of 'editable' chassis cells is critical for accelerating industrialization. This Research Topic aims to discuss the possibility that marine bacteria and microalgae could serve as synthetic biology chassis. The goal of the Topic is to gather creative ideas and cutting-edge research in order to throw more light on marine biomanufacturing in the context of a sustainable economy and ecosystem.
The current Research Topic intends to investigate marine bacteria and microalgae as synthetic biology host organisms, which are the foundation for achieving the objective of 'Building-to-Understand' and 'Building-to-Apply.' Identification and characterization of core components, such as parts of enzymes, genetic circuits, metabolic pathways, etc., is critical for 'Building-to-Understand,' as is determining the interaction between genotype and superior phenotype, and the underlying regulatory mechanisms, as well as investigating the universal patterns of matter and energy fluxes in chassis cells. Development of genome-editing technologies, rational design and creation of metabolic pathways, and compatibility of new biological entities into integrated systems are all part of the 'Building-to-Apply' category.
This Research Topic will include, but is not limited to, the following topics:
• Marine creature bioprospecting and profiling for synthetic biology applications
• Development of genome-editing tools for marine organisms
• Robustness of marine host organisms and compatibility with industrial systems
• Characterization of industrially relevant traits in marine bacteria and microalgae
• Biosynthesis of high-value products in marine organisms and metabolic engineering strategies
The current Research Topic intends to investigate marine bacteria and microalgae as synthetic biology host organisms, which are the foundation for achieving the objective of 'Building-to-Understand' and 'Building-to-Apply.' Identification and characterization of core components, such as parts of enzymes, genetic circuits, metabolic pathways, etc., is critical for 'Building-to-Understand,' as is determining the interaction between genotype and superior phenotype, and the underlying regulatory mechanisms, as well as investigating the universal patterns of matter and energy fluxes in chassis cells. Development of genome-editing technologies, rational design and creation of metabolic pathways, and compatibility of new biological entities into integrated systems are all part of the 'Building-to-Apply' category.
This Research Topic will include, but is not limited to, the following topics:
• Marine creature bioprospecting and profiling for synthetic biology applications
• Development of genome-editing tools for marine organisms
• Robustness of marine host organisms and compatibility with industrial systems
• Characterization of industrially relevant traits in marine bacteria and microalgae
• Biosynthesis of high-value products in marine organisms and metabolic engineering strategies
Keywords: marine bacteria, marine microalgae, synthetic biology, genome-editing, Biosynthesis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
