Frontiers | Accelerating Cancer Biology through Spatial-Omics Approaches

Accelerating Cancer Biology through Spatial-Omics Approaches

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ORIGINAL RESEARCH

Published on 04 Jan 2023

The relevance between hypoxia-dependent spatial transcriptomics and the prognosis and efficacy of immunotherapy in claudin-low breast cancer

Huizhi Sun
Yanlei Li
Yanhui Zhang
Xiulan Zhao
Xueyi Dong
Yuhong Guo
Jing Mo
Na Che
Xinchao Ban
4 more
Danfang Zhang

The relevance between hypoxia-dependent spatial transcriptomics and the prognosis and efficacy of immunotherapy in claudin-low breast cancer

doi 10.3389/fimmu.2022.1042835

2,720 views
7 citations

METHODS

Published on 19 Dec 2022

Spatial heterogeneity of cancer associated protein expression in immunohistochemically stained images as an improved prognostic biomarker

Henrik Failmezger
Harald Hessel
Ansh Kapil
Günter Schmidt
Nathalie Harder

Spatial heterogeneity of cancer associated protein expression in immunohistochemically stained images as an improved prognostic biomarker

doi 10.3389/fonc.2022.964716

1,298 views
2 citations

ORIGINAL RESEARCH

Published on 05 Dec 2022

Quantitative spatial evaluation of tumor-immune interactions in the immunotherapy setting of metastatic melanoma lymph nodes

Rachel L. G. Maus
Alexey A. Leontovich
Raymond M. Moore
Zachary Fogarty
Ruifeng Guo
Tara M. Davidson
Burak Tekin
Chathu Atherton
Jill M. Schimke
2 more
Svetomir N. Markovic

Quantitative spatial evaluation of tumor-immune interactions in the immunotherapy setting of metastatic melanoma lymph nodes

doi 10.3389/fimmu.2022.1024039

2,880 views
4 citations

TECHNOLOGY AND CODE

Published on 13 Oct 2022

Automated multimodal fluorescence microscopy for hyperplex spatial-proteomics: Coupling microfluidic-based immunofluorescence to high resolution, high sensitivity, three-dimensional analysis of histological slides

Laura Furia
Simone Pelicci
Federica Perillo
Maddalena M. Bolognesi
Pier Giuseppe Pelicci
Federica Facciotti
Giorgio Cattoretti
Mario Faretta

Automated multimodal fluorescence microscopy for hyperplex spatial-proteomics: Coupling microfluidic-based immunofluorescence to high resolution, high sensitivity, three-dimensional analysis of histological slides

doi 10.3389/fonc.2022.960734

2,421 views
7 citations

REVIEW

Published on 29 Jul 2022

Next-Generation Pathology Using Multiplexed Immunohistochemistry: Mapping Tissue Architecture at Single-Cell Level

Francesca Maria Bosisio
Yannick Van Herck
Julie Messiaen
Maddalena Maria Bolognesi
Lukas Marcelis
Matthias Van Haele
Giorgio Cattoretti
Asier Antoranz
Frederik De Smet

Next-Generation Pathology Using Multiplexed Immunohistochemistry: Mapping Tissue Architecture at Single-Cell Level

doi 10.3389/fonc.2022.918900

8,836 views
28 citations

ORIGINAL RESEARCH

Published on 01 Jun 2022

Differential Gene Expression and Weighted Correlation Network Dynamics in High-Throughput Datasets of Prostate Cancer

Taj Mohammad
Prithvi Singh
Deeba Shamim Jairajpuri
Lamya Ahmed Al-Keridis
Nawaf Alshammari
Mohd. Adnan
Ravins Dohare
Md Imtaiyaz Hassan

Differential Gene Expression and Weighted Correlation Network Dynamics in High-Throughput Datasets of Prostate Cancer

doi 10.3389/fonc.2022.881246

5,096 views
19 citations

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Frontiers in Oncology

Frontiers in Oncology

Cancer Molecular Targets and Therapeutics
Cancer Immunity and Immunotherapy

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Frontiers in Immunology
- Cancer Immunity and Immunotherapy
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