Advances in Imaging and Imaging-Directed Interventions in Hepatic Cancers

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About this Research Topic

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Background

Cancers of the liver and intrahepatic bile duct account for over 40,000 diagnosed cases of cancer worldwide each year, which is roughly 2% of all cancer diagnoses. Despite this, they are estimated to make up 5% of cancer deaths each year, and the rate at which these diagnoses are made is increasing year-on-year by over 1.5% annually. Considering these figures it is clear that more needs to be done in order to identify cases sooner, or to make more accurate predictions regarding a patient's prognosis. There is also a need to bolster the therapeutic methods we have for treating these cancers in order to decrease mortality rates.

Current imaging practices used to identify and monitor cancers of the liver include Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Ultrasound, and more recently hybrid Positron Emission Tomography (PET) methodologies with CT or MRI. Imaging directed methods of treatment or ablation techniques are also becoming more commonplace in modern practise, including Radiofrequency Hyperthermia (RFH), as well as nanoparticle delivery system therapies. However, as these techniques are still in infancy the full benefit remains to be seen. We believe further research could uncover the full potential of these techniques in the context of hepatic cancers.

Due to the vital role of the liver within the body, making well informed decisions regarding interventions is pivotal for clinicians in order to maintain quality of life standards for patients living with liver cancer after intervention by preserving organ function. Methodologies to refine existing and identify novel imaging techniques can have a hugely positive effect on the treatment of this disease.

We welcome Original Research, leading-edge Reviews, and Clinical Trials related but not limited to the aspects below:
- Novel imaging techniques proving beneficial in diagnosis of liver cancers
- Using imaging techniques to more accurately stage liver cancers
- Identifying metastasis using advanced cancer imaging techniques
- Improving patient outcomes with more accurate prognoses and subsequent individualized interventions as a result of advanced imaging techniques
- Innovations in cancer directed therapies for hepatic cancers

Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.

Keywords: imaging, advanced, hepatic, liver, tumors, cancer, image directed intervention, advanced imaging, advances

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