About this Research Topic
Given the success of Volume I of this Research Topic, we are pleased to announce the launch of Volume II of The Pivotal Role of Oral Microbiota Dysbiosis and Microbiota-host Interactions in Diseases .
The oral microbiota represents an important part of the human microbiota. The oral microbiota dysbiosis, characterized by impaired diversity and/or function of microflora, is one of the most important factors that can lead to oral diseases, pathologically bacterial translocation and systemic infection. The last two decades have witnessed tremendous new insights into the mechanisms that link microbiota dysbiosis with diseases, including periodontitis, diabetes, cancer, and rheumatoid arthritis. Oral microbiota dysbiosis results in an imbalance in oral microbial homeostasis, while specific oral microbiota induces inflammatory response, and influences host biological processes (such as cell migration, cell apoptosis, cell proliferation, and autophagy), leading to many pathologies. The microbiota communicates with the host via various signalling pathways, epigenetic mechanisms, and biomolecules. Novel strategies targeting these processes are important for disease prevention and treatment.
The aim of the present Research Topic is to assemble Original Research articles and Reviews addressing the questions related to the pivotal role of oral microbiota dysbiosis and microbiota-host interactions in oral and systemic diseases, and novel diagnosis and therapeutic strategies against diseases caused by oral microbiota dysbiosis. We welcome submissions on the subtopics below:
• Novel findings of oral microbiota dysbiosis and microbiota-host interactions in diseases.
• Regulation of host biological processes (such as cell migration, cell apoptosis, cell proliferation and autophagy) by oral microbial proteins in diseases.
• The epigenetic mechanisms in modulating oral microbiota-host interactions.
• New compounds or novel approaches, such as biological physics, nanotechnology, next-generation sequencing, in diagnosis or treatment of diseases caused by oral microbiota dysbiosis.
The oral microbiota represents an important part of the human microbiota. The oral microbiota dysbiosis, characterized by impaired diversity and/or function of microflora, is one of the most important factors that can lead to oral diseases, pathologically bacterial translocation and systemic infection. The last two decades have witnessed tremendous new insights into the mechanisms that link microbiota dysbiosis with diseases, including periodontitis, diabetes, cancer, and rheumatoid arthritis. Oral microbiota dysbiosis results in an imbalance in oral microbial homeostasis, while specific oral microbiota induces inflammatory response, and influences host biological processes (such as cell migration, cell apoptosis, cell proliferation, and autophagy), leading to many pathologies. The microbiota communicates with the host via various signalling pathways, epigenetic mechanisms, and biomolecules. Novel strategies targeting these processes are important for disease prevention and treatment.
The aim of the present Research Topic is to assemble Original Research articles and Reviews addressing the questions related to the pivotal role of oral microbiota dysbiosis and microbiota-host interactions in oral and systemic diseases, and novel diagnosis and therapeutic strategies against diseases caused by oral microbiota dysbiosis. We welcome submissions on the subtopics below:
• Novel findings of oral microbiota dysbiosis and microbiota-host interactions in diseases.
• Regulation of host biological processes (such as cell migration, cell apoptosis, cell proliferation and autophagy) by oral microbial proteins in diseases.
• The epigenetic mechanisms in modulating oral microbiota-host interactions.
• New compounds or novel approaches, such as biological physics, nanotechnology, next-generation sequencing, in diagnosis or treatment of diseases caused by oral microbiota dysbiosis.
Keywords: Oral Microbiota, Dysbiosis, Microbiota-host Interactions, Volume II
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
