About this Research Topic
Fatty liver diseases (FLD) have recently attracted much attention due to the increasing prevalence and liver‐related morbidity and mortality. The NAFLD (Non-alcoholic Fatty Liver Disease) refers to the FLD without an excessive alcohol intake or other etiology of chronic liver disease.
Recently, in 2020, a consensus meeting of international experts proposed to replace the NAFLD with MAFLD (Metabolic dysfunction‐Associated Fatty Liver Disease). However, whether the definition "MAFLD" is better than NAFLD, in the identification and management of Fatty Liver Disease patients at high risk of disease progression, is yet to be determined.
As “MAFLD” has recently been coined, there are still a plethora of unexplained and unanswered questions. In the light of this; we need to look at the pieces of evidence comparing the difference in genetic, pathophysiological, clinical, and public health research between MAFLD and NAFLD.
In this Research Topic, we welcome investigators to contribute with their original research or review articles that will help to understand the FLD, especially the MAFLD.
Welcome topics include but are not limited to the following:
• The genetic features and differenced between NAFLD/MAFLD.
• The epidemiology of MAFLD.
• The role of liver histology in the diagnosis and management of MAFLD.
• The role concomitant alcohol consumption, viral hepatitis, and other etiologies play in the epidemiology, pathophysiology and clinical characteristics of MALFD.
Recently, in 2020, a consensus meeting of international experts proposed to replace the NAFLD with MAFLD (Metabolic dysfunction‐Associated Fatty Liver Disease). However, whether the definition "MAFLD" is better than NAFLD, in the identification and management of Fatty Liver Disease patients at high risk of disease progression, is yet to be determined.
As “MAFLD” has recently been coined, there are still a plethora of unexplained and unanswered questions. In the light of this; we need to look at the pieces of evidence comparing the difference in genetic, pathophysiological, clinical, and public health research between MAFLD and NAFLD.
In this Research Topic, we welcome investigators to contribute with their original research or review articles that will help to understand the FLD, especially the MAFLD.
Welcome topics include but are not limited to the following:
• The genetic features and differenced between NAFLD/MAFLD.
• The epidemiology of MAFLD.
• The role of liver histology in the diagnosis and management of MAFLD.
• The role concomitant alcohol consumption, viral hepatitis, and other etiologies play in the epidemiology, pathophysiology and clinical characteristics of MALFD.
Keywords: NAFLD, MAFLD, fatty liver disease, outcome, epidemiology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
