About this Research Topic
This Research Topic aims to provide a comprehensive view of topical areas related to rare dyslipidemias in the form of research articles, case reports and review articles. Case reports will only be accepted if they highlight unique cases of human or animal patients that present with an unexpected/diagnosis, treatment outcome, or clinical course. We encourage submissions that show the use of animal models, cell based models, or intersection of -omics technologies to improve discoveries about rare dyslipidemias to further our knowledge about predictive and precision medicine. In addition, submissions pertaining to pathophysiological mechanisms of novel drug targets such as ANGPTL3, novel therapies like MTP-, apoB- and PCSK9 inhibitors, HDLmimetic infusions and gene editing (CRISPR/Cas9) and management of rare dyslipidaemia are also welcome.
The following themes will be covered in this collection:
1. Genetic Background of Rare Dyslipidemias
2. Epidemiology of Rare Dyslipidemias
3. Screening and Diagnostics for Rare Dyslipidemias
4. Genetic Diseases and Rare Genetic Syndromes with Dyslipidemias
5. Current and Future Therapies for Rare Dyslipidemias
Topic Editor Robert Hegele received financial support from Acasti, Aegerion, Akcea/Ionis, Amgen, Arrowhead, HLS Therapeutics, Novartis, Pfizer, Regeneron and Sanofi and Topic Editor
Segreteria Catapano received financial support from Aegerion, Amgen, Amryt, Astrazeneca, Bayer, Daiichi-Sankyo, Eli Lilly, Genzyme, Ionis Pharmaceutical, Kowa, Mediolanum, Medscape, Menarini, Merck, Mylan, Novartis, PeerVoice, Pfizer, Recordati, Regeneron, Sanofi,
Sigma-Tau, The Corpus. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Keywords: Rare Dyslipidemia, hypercholesterolemia, hypocholesterolemia, hypertriglyceridemia, inborn errors of metabolism, cardiovascular disorders, rare genetic syndromes
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.