Molecular Imaging in Retinal Diseases

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About this Research Topic

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Background

Retinal diseases include a wide variety of diseases occurring in the retina, caused by diverse pathogenic processes such as neovascularization, infections/inflammation, trauma, drug-induced toxicity, genetic mutation, and even aging. Common retinal diseases include age-related macular degeneration, diabetic retinopathy, retinal detachment, epiretinal membrane, and retinitis pigmentosa. Visual impairment secondary to retinal diseases is a global public health problem and can be a significant economic burden to our society due to loss of labor productivity. Therefore, early diagnosis and appropriate management is required for the diseases.

Advances in clinical imaging have enabled visualization of the retina at an unprecedented resolution. However, most of the imaging modalities detect the disease after structural changes caused by diverse pathologic processes become apparent. Molecular imaging has provided a window on dynamic pathogenic processes using molecular biomarkers in human diseases and thus may enable visualization of pathogenic processes prior to overt structural changes. This imaging may be helpful for achieving the goal of early detection in retinal diseases.

Recently, there have been advances in the field of molecular imaging in retinal diseases. These have shown promising results for early detection of retinal diseases and earlier intervention for the pathogenic processes.
For this research topic, we welcome original articles and expert reviews about the study on the advances in molecular imaging in retinal diseases.

Welcome manuscripts include Original Research, Reviews, mini-reviews, methods, perspectives and case reports on the following themes:

• New advances in the use of already reported molecular imaging techniques to identify molecular biomarkers and molecular mediators in retinal diseases.
• Identification of new molecular imaging techniques and new approaches to identify pathogenic biomarkers in retinal diseases.
• Progresses in molecular imaging techniques with the final goal of improving the diagnosis of retinal diseases at the molecular level.
• Description of the molecular pathogenic processes of retinal diseases.
• Clinical and pre-clinical research.

The scope of this Research Topic is to improve the early detection of retinal diseases and to identify new therapeutic targets thanks to ophthalmic imaging techniques, with the final aim of improving the outcome of the disease in the patients.

Keywords: Molecular imaging, retinal diseases, age-related macular degeneration, diabetic retinopathy, retinal vein occlusion, retinal artery occlusion, retinopathy of prematurity, epiretinal membrane, retinitis pigmentosa

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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