Neonatal and pediatric brain injuries are caused by several causes, such as traumatic injury, stroke, hypoxic-ischemic encephalopathy, intraventricular hemorrhage, irradiation, and infection, and they place a great burden not only on the infant but also on the family. Several conventional therapies are used for brain injuries, and a therapeutic effect has been established to a certain extent. However, complete neurological recovery is still difficult, and neurological sequelae often remain. Thus, additional novel treatments are needed for such injuries. A large number of basic research and clinical studies that use new drugs, cell therapy, and rehabilitation / interventions have been conducted, and their feasibility and efficacy have been reported. These recent advances of novel therapeutics are promising, in regard to treating neonatal and pediatric brain injury.
To provide an appropriate treatment for neonates and children, a balanced and comprehensive expertise in developmental therapeutics is required. The purpose of this Research Topic is to feature research about new therapeutics for neonatal and pediatric brain injuries in the seeding stage, which will be key to new treatment strategies and can develop into clinical research in the future. The project also aims to bring together basic and clinical evidence for many of the treatments currently underway for brain injury, to establish a more robust treatment protocol. On this basis, both Review and Original Research articles addressing such topics are welcome in this collection.
The editors envisage receiving contributions that may cover research about novel treatments or therapeutic strategies currently in the late phase of development (near approval by FDA or equivalent). We propose the following thematic areas, but we will welcome other relevant contributions as well.
1. Epidemiology and new findings in relation to Neonatal and Pediatric Brain Injury
2. Appropriate treatment strategy for Neonatal and Pediatric Brain Injury
3. Upcoming or ongoing clinical studies of Neonatal and Pediatric Brain Injury
4. Novel treatments for Neonatal and Pediatric Brain Injury
5. Updates on the prognosis of brain injuries in neonates and children.
Neonatal and pediatric brain injuries are caused by several causes, such as traumatic injury, stroke, hypoxic-ischemic encephalopathy, intraventricular hemorrhage, irradiation, and infection, and they place a great burden not only on the infant but also on the family. Several conventional therapies are used for brain injuries, and a therapeutic effect has been established to a certain extent. However, complete neurological recovery is still difficult, and neurological sequelae often remain. Thus, additional novel treatments are needed for such injuries. A large number of basic research and clinical studies that use new drugs, cell therapy, and rehabilitation / interventions have been conducted, and their feasibility and efficacy have been reported. These recent advances of novel therapeutics are promising, in regard to treating neonatal and pediatric brain injury.
To provide an appropriate treatment for neonates and children, a balanced and comprehensive expertise in developmental therapeutics is required. The purpose of this Research Topic is to feature research about new therapeutics for neonatal and pediatric brain injuries in the seeding stage, which will be key to new treatment strategies and can develop into clinical research in the future. The project also aims to bring together basic and clinical evidence for many of the treatments currently underway for brain injury, to establish a more robust treatment protocol. On this basis, both Review and Original Research articles addressing such topics are welcome in this collection.
The editors envisage receiving contributions that may cover research about novel treatments or therapeutic strategies currently in the late phase of development (near approval by FDA or equivalent). We propose the following thematic areas, but we will welcome other relevant contributions as well.
1. Epidemiology and new findings in relation to Neonatal and Pediatric Brain Injury
2. Appropriate treatment strategy for Neonatal and Pediatric Brain Injury
3. Upcoming or ongoing clinical studies of Neonatal and Pediatric Brain Injury
4. Novel treatments for Neonatal and Pediatric Brain Injury
5. Updates on the prognosis of brain injuries in neonates and children.