Migraine is a complex primary headache with high prevalence and disability. In current clinical practice, the diagnosis of migraine is still based on clinical criteria that may not reflect the whole picture, such as a possible genetic component, immunological factors, altered cerebral structure, dysfunction in cerebral circuits, metabolism and blood perfusion. In patients with atypical symptoms, a definite diagnosis may be difficult, resulting in delayed diagnosis and treatment. Therefore, it is necessary to pay more attention to auxiliary biomarkers.
In most clinical application scenarios, biomarkers are considered as tools for early diagnosis, which actually have a wide range of clinical applications, including diagnosis, subtype classification, prognosis, and therapeutic effect evaluation. Due to the high heterogeneity in migraine, migraine-specific, individualized and multi-perspective biomarkers could significantly advance precision medicine in migraine. On the other hand, clinically reliable biomarkers could elucidate the pathophysiology of migraine and advance new therapeutic strategies.
The aim of this Research Topic is to identify potential biomarkers for migraine and to further investigate the association of biomarkers with diagnosis, stratification, prognosis and therapy. We welcome submissions of Original Research and Review on the following topics:
- Biochemical biomarkers for migraine
- Genetic biomarkers for migraine
- Multi-omics biomarkers for migraine
- Neuroimaging biomarkers for migraine
- Provocation biomarkers for migraine
- Biomarkers for migraine as prognostic indicators
- Biomarkers for migraine classification
- Biomarkers for evaluation of therapeutic effects in migraine
Migraine is a complex primary headache with high prevalence and disability. In current clinical practice, the diagnosis of migraine is still based on clinical criteria that may not reflect the whole picture, such as a possible genetic component, immunological factors, altered cerebral structure, dysfunction in cerebral circuits, metabolism and blood perfusion. In patients with atypical symptoms, a definite diagnosis may be difficult, resulting in delayed diagnosis and treatment. Therefore, it is necessary to pay more attention to auxiliary biomarkers.
In most clinical application scenarios, biomarkers are considered as tools for early diagnosis, which actually have a wide range of clinical applications, including diagnosis, subtype classification, prognosis, and therapeutic effect evaluation. Due to the high heterogeneity in migraine, migraine-specific, individualized and multi-perspective biomarkers could significantly advance precision medicine in migraine. On the other hand, clinically reliable biomarkers could elucidate the pathophysiology of migraine and advance new therapeutic strategies.
The aim of this Research Topic is to identify potential biomarkers for migraine and to further investigate the association of biomarkers with diagnosis, stratification, prognosis and therapy. We welcome submissions of Original Research and Review on the following topics:
- Biochemical biomarkers for migraine
- Genetic biomarkers for migraine
- Multi-omics biomarkers for migraine
- Neuroimaging biomarkers for migraine
- Provocation biomarkers for migraine
- Biomarkers for migraine as prognostic indicators
- Biomarkers for migraine classification
- Biomarkers for evaluation of therapeutic effects in migraine