Assessment of Osteoporotic Fractures and Risk Prediction

With the aging of the population, osteoporosis and osteoporosis-related fractures have become a growing public health problem due to the high disability and fatality. Osteoporotic fractures, especially hip fractures, lead to a significant decline in the quality of life. Within 1 year after the occurrence of hip fractures, 21%-30% of patients lost their lives to various complications. As a result, osteoporosis treatment and nursing need a lot of manpower and material resources, which have a serious impact on society, the economy and the medical system. However, the overall diagnosis rate of osteoporosis is still low, and many patients were not diagnosed with osteoporosis until fractures occurred. Therefore, it is urgent to accurately predict and identify the high-risk population of fracture to prevent or reduce the occurrence of osteoporotic fractures. Many guidelines recommended using FRAX to predict the risk of fracture in the adult population. This tool assesses the probability of hip and major osteoporotic fractures over the next 10 years based on clinical risk factors with/without BMD of the femoral neck. Other tools assessing fracture risk include the IOF test on osteoporosis risk in a minute, OSTA, SCORE, and so on.

This Research Topic aims to provide insight into the etiology and pathogenesis of osteoporotic fractures, such as the connections between bone mineral density, bone mineral content, and muscle, focusing on clinical research related to the diagnosis, prevention, treatment and monitoring of osteoporotic fracture.

This Research Topic provides not only cutting-edge scientific advances on the basic and clinical research of osteoporosis, but also pays attention to the translation of basic research results into new developments of diagnostics for osteoporotic fractures, as well as epidemiology and risk prediction of fractures.

We welcome the submission of original research, reviews/mini-reviews, perspectives, and opinion articles on the contribution of the Assessment of Osteoporotic Fractures and Risk Prediction by doctors in endocrine and related fields. We accept contributions related to, but not limited to, the following themes:
• Novel prediction and screening tools of osteoporotic fractures and introduction of fracture risk prediction tools.
• Diagnosis, prevention, treatment, monitoring and epidemiology of osteoporotic fractures and the application of the prediction and screening tools in them.
• Clinical characteristics of osteoporotic fractures patients for the development of tools.