About this Research Topic
The development of new bioinformatics methods and models, e.g. machine-learning (ML) approaches, is of great value for studying cis-regulatory code. However, we need plant biologists to apply new, as well as classical, approaches to study cis-regulatory code behind particular aspects of plant development and physiology. We encourage contributions on plant cis-regulatory elements in silico, in vitro, in vivo, or in planta.
The collection will include Original Research, Reviews, and Opinions about the following topics:
- study of a transcription factor binding profiles and targets in plants;
- analysis of cis-regulatory syntax and search for composite elements and modules;
- exploration of the repertoire of cis-elements behind a transcriptional response to environmental conditions or treatments;
- study of conservation in cis-regulatory sequences;
- experimental validation of cis-regulatory elements functionality;
- development and application of new methods to infer and annotate the cis-regulatory code.
Keywords: cistrome, regulomics, ChIP-Seq, DAP-Seq, ATAC-Seq, STAR-seq, SNP, PWM, binding site, composite cis-elements, chromatin, omics, CRISPR, genome editing, transcription factor
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.