About this Research Topic
Juvenile systemic connective tissue disease is an umbrella term encompassing various juvenile-onset chronic autoimmune disorders: juvenile systemic lupus erythematosus, juvenile dermatomyositis, juvenile systemic scleroderma, juvenile localized scleroderma, juvenile mixed connective tissue disease and juvenile Sjögren syndrome. Children with these chronic autoimmune disorders manifest symptoms and signs related to various organ systems. Presentation may be quite different from that in adults with the same condition.
The incidence and prevalence of these disorders in children are extremely low comparing to adult counterparts. However, since the reported incidence and prevalence of juvenile systemic connective tissue diseases have been steadily increasing over the years, juvenile-onset form may be more widespread than thought and considerably underdiagnosed in a significant number of children.
systemic connective tissue diseases are limited. There is a great need for an article collection that could highlight the recent advances in juvenile systemic connective tissue diseases. Raising the awareness of medical community particularly the pediatricians and pediatric rheumatologists regarding these overlooked medical conditions, would possibly prevent the diagnostic delays and enable early treatment.
The aim of this special issue is to discuss the recent advances in pathogenesis, discovery of novel biomarkers, clinical aspects and treatment options in juvenile systemic connective tissue diseases over the last 5-years.
We will consider original research articles, review articles, case reports, and letters on juvenile systemic connective tissue diseases
Potential topics that we would like to include are;
● Update on pathophysiology
● Current incidence and prevalence
● Comparison of pediatric and adult-onset systemic connective tissue diseases
● Classification criteria
● Novel biomarkers
● Imaging
● Treatment options and treatment responses
● Outcome
The incidence and prevalence of these disorders in children are extremely low comparing to adult counterparts. However, since the reported incidence and prevalence of juvenile systemic connective tissue diseases have been steadily increasing over the years, juvenile-onset form may be more widespread than thought and considerably underdiagnosed in a significant number of children.
systemic connective tissue diseases are limited. There is a great need for an article collection that could highlight the recent advances in juvenile systemic connective tissue diseases. Raising the awareness of medical community particularly the pediatricians and pediatric rheumatologists regarding these overlooked medical conditions, would possibly prevent the diagnostic delays and enable early treatment.
The aim of this special issue is to discuss the recent advances in pathogenesis, discovery of novel biomarkers, clinical aspects and treatment options in juvenile systemic connective tissue diseases over the last 5-years.
We will consider original research articles, review articles, case reports, and letters on juvenile systemic connective tissue diseases
Potential topics that we would like to include are;
● Update on pathophysiology
● Current incidence and prevalence
● Comparison of pediatric and adult-onset systemic connective tissue diseases
● Classification criteria
● Novel biomarkers
● Imaging
● Treatment options and treatment responses
● Outcome
Keywords: Juvenile systemic lupus erythematosus, Juvenile dermatomyositis, Juvenile systemic scleroderma, Juvenile localized scleroderma, Juvenile mixed connective tissue disease, Juvenile Sjögren syndrome
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