Endocrine Regulation of Mineral Ions and their Relevance to Metabolic Diseases

Metabolic disorders, including obesity, type 2 diabetes, insulin resistance, and cardiovascular disease are alarmingly rising around the globe and causing major health problems leading to significant morbidity and mortality. Many essential nutrients and minerals play a vital role in maintaining metabolic homeostasis. Phosphate, calcium, magnesium, zinc, selenium, iron, and vitamins are required for controlling the homeostatic balance of cells and tissue functions. Earlier works by Hartman et al. have shown that salivary phosphate levels can predict the genesis of obesity in children. Despite progress in our understanding of pathomechanism of metabolic diseases, there are knowledge gaps of how dysregulations of various minerals and nutrients are triggering and propagating metabolic disorders.

This Research Topic welcomes the submission of original manuscripts (unpublished research works), updated reviews (of the existing literate), and brief commentaries (on emerging areas of mineral ion metabolism). The idea is to broadly and holistically provide current understandings of endocrine regulation of mineral ion metabolism with metabolic relevance.

We welcome the submission of manuscripts related to:
- Endocrine regulation of mineral ions in health and diseases
- Mineral ion metabolism and metabolic diseases
- Mineral ion metabolism and inflammation
- Mineral ion metabolism and aging
- Mineral ion metabolism and cancer
- Phosphate containing beverages and metabolic diseases