Mechanisms of Wound Healing

Wound healing is a complex process that requires numerous populations of cells to work in synergy to remove pathogens, rapidly vascularize to provide oxygenation, followed by closure and remodeling of the wound site. Defining the interplay of mechanisms between the cellular populations will assist in better understanding wound healing, in particular during the development of chronic wounds, as observed in the ageing population. Additionally, this will allow for the development of novel therapies in assisting wound healing, in particular the use of exogenous topical agents and/or administration of stem cell therapies.

The aim of the current Research Topic is to cover promising, recent, and novel research trends in wound healing. Areas to be covered in this Research Topic may include, but are not limited to:

• Development of stem cell therapies
• Development of wound scaffolds
• Biomaterials in wound healing
• Therapeutic strategies of wound healing
• Advanced genomic and proteomic analysis of wounds
• New models for investigating mechanisms of wound healing
• Vascularization of chronic wounds
• Single-cell RNA sequencing
• Spatial omics
• Wound regeneration using stem cell therapies
• Novel biomaterials and scaffolds for wound healing
• Emerging technologies in wound care
• Animal models in wound healing research
• Biomarkers for wound healing