About this Research Topic
In this special issue, we are interested in topics focused on role of non-coding RNAs in development, host-pathogen interaction, disease biology and therapeutic approaches.
We welcome Original Research, Methods, Review and Brief Report.
The themes that we wish to include but are not limited to the following:
• Identify novel non-coding RNAs across species and its role in development;
• Identify functional variations within non-coding RNA and their implication in diseases;
• Develop computational tools, databases and algorithms to identify non-coding RNA variations;
• Exploring the effect of non-coding RNA variations on RNA-RNA interactions, namely, miRNA-mRNA, miRNA-Alu, miRNA-lncRNA-mRNA, etc
• Exploring how variations within non-coding RNAs can affect their structure, stability and processing;
• Discover the potential of non-coding RNAs as biomarkers in liquid biopsies, namely, circulating tumor cells, extracellular vesicles, and so forth;
• Targeting non-coding RNA and their disease associated variants for therapeutic approaches, namely, by small molecules, genome editing, RNA editing etc;
• Identify the effect of non-coding RNA variations in the host-pathogen response
Keywords: Non-coding RNA, Variation, RNA editing, Development, Cancer, Extracellular vesicles, Genome editing, CRISPR-Cas9, Host-pathogen interaction
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.