About this Research Topic
Studies regarding the effect of drugs on structural and functional components of the synaptic region, receptor-receptor interactions, and enzyme-receptor interactions at synaptic region will be welcomed. It is expected that contributions regarding the influence of drugs on synaptic plasticity and brain mitochondrial bioenergetics will shed light on the neurotransmission processes.
Approaches at cellular and molecular levels may elucidate the relationship between neuron structure and function. A final goal is to understand the pathogenesis of neurological illness.
Areas of interest to this project include, but are not limited to:
• Effect of drugs on synaptic protein complexes.
• Bidirectional changes in receptor-receptor interactions at synapses by drug administration.
• Changes in enzyme-receptor interactions at synapses by drug administration.
• Effects of drugs on brain mitochondrial bioenergetics and free radical production.
• Alteration of mitochondrial functionality by drug administration concomitant with impairment of neurotransmission processes.
• Drug effects on synaptic adhesivity and remodeling.
Types of manuscripts:
• Original research articles
• Review articles
Keywords: central action drugs, central neurotransmission, enzyme-receptor interactions, receptor-receptor interactions, mitochondrial bioenergetics, mitochondrial functionality, oxidative stress, synaptic adhesivity
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.