About this Research Topic
Biosensors and bioassays are tasked with identifying and quantifying target analytes in practical matrices containing complex mixtures of homologous analytes. The greatest roadblock to successful detection is the low abundance presence of target analytes, which is fairly common in the early stage of various diseases, disorders or contaminations. Detection strategies often affect the limit of detection, the response time and the linear range. Various sample enrichment and signal amplification approaches are often adopted in co-ordination with detection strategies to attain satisfactory limit of detection, specificity and turnaround time. The goal of this Research Topic is to provide a forum sharing recent research and novel ideas on strategies for target analyte recognition, enrichment and detection based on advanced materials, devices and methods. Besides the mentioned aspects, this Topic also focuses on other key techniques in biosensor/bioassay development, optimization and application.
Types of manuscripts include Original Research, Review, Mini-Reviews and Perspective articles. Themes to be investigated may include, but are not limited to:
Bio-probe and chem-probe synthesis, isolation and evaluation
Strategies for target analyte enrichment and concentration
Advanced signal amplification and transduction strategies
Biosensor construction with novel materials and structures
High sensitive biosensors with different signal read-out
CRISPR/Cas powered biosensors
Keywords: Analytes, Low Abundance, Biosensors, Biodetection, Analyte Enrichment, Analyte Concentration
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.