About this Research Topic
Sepsis is a global public health problem due to its high incidence and accompanying mortality, morbidity and financial burden for families and society. Children represent more than half of the cases of sepsis in the world. Despite numerous efforts, mortality from sepsis in children remains high: 1 in 4 children with severe sepsis die. Mortality is associated, among other factors, with delay in diagnosis and treatment.
On behalf of the XVII International Sepsis Forum coordinated by Latin America Sepsis Institute (LASI) on May 20-21, 2021, the objective of this Research Topic is to describe where we are in pediatric and neonatal sepsis, and call to actions that can provide an improvement in the prognosis of children with sepsis, presenting the challenges and potential solutions.
In this Research Topic, we intend to describe an overview of pediatric sepsis. Through review studies and clinical trials, we will discuss the epidemiological aspects of pediatric and neonatal sepsis and where we are in the diagnosis and treatment of pediatric sepsis. Our goal is to draw attention to the challenges of sepsis in the pediatric population and what the perspectives are.
The scope of this topic covers several topics, such as:
• Diagnosis and treatment of pediatric and neonatal sepsis
• Antimicrobial therapy in pediatric sepsis
• Fluid resuscitation in pediatric sepsis
• Pathophysiology of pediatric and neonatal sepsis
• Pediatric and neonatal sepsis prevention measures (immunization)
• Quality improvement initiatives in pediatric sepsis
• Early goal-oriented therapy in the emergency room: what every pediatrician needs to know
• Nutrition in pediatric and neonatal sepsis
• Multiple organ and system dysfunction in critically ill children
• The role of the endothelium in sepsis
• The role of biomarkers in pediatric and neonatal sepsis
• Refractory shock in pediatric and neonatal sepsis
• Pediatric sepsis research: where are we and where are we going?
On behalf of the XVII International Sepsis Forum coordinated by Latin America Sepsis Institute (LASI) on May 20-21, 2021, the objective of this Research Topic is to describe where we are in pediatric and neonatal sepsis, and call to actions that can provide an improvement in the prognosis of children with sepsis, presenting the challenges and potential solutions.
In this Research Topic, we intend to describe an overview of pediatric sepsis. Through review studies and clinical trials, we will discuss the epidemiological aspects of pediatric and neonatal sepsis and where we are in the diagnosis and treatment of pediatric sepsis. Our goal is to draw attention to the challenges of sepsis in the pediatric population and what the perspectives are.
The scope of this topic covers several topics, such as:
• Diagnosis and treatment of pediatric and neonatal sepsis
• Antimicrobial therapy in pediatric sepsis
• Fluid resuscitation in pediatric sepsis
• Pathophysiology of pediatric and neonatal sepsis
• Pediatric and neonatal sepsis prevention measures (immunization)
• Quality improvement initiatives in pediatric sepsis
• Early goal-oriented therapy in the emergency room: what every pediatrician needs to know
• Nutrition in pediatric and neonatal sepsis
• Multiple organ and system dysfunction in critically ill children
• The role of the endothelium in sepsis
• The role of biomarkers in pediatric and neonatal sepsis
• Refractory shock in pediatric and neonatal sepsis
• Pediatric sepsis research: where are we and where are we going?
Keywords: Pediatric Sepsis, Child, Diagnosis, Treatment, Critical Illness
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
