About this Research Topic
Loss of muscle mass and increased intramuscular fibrosis characterize both aging sarcopenia and muscular dystrophy. Research has shown that these two conditions also share some pathophysiological mechanisms including mitochondrial dysfunction, increased apoptosis, abnormal modulation of autophagy, decline in satellite cells, increased generation of reactive oxygen species, and modification of signalling and stress response pathways.
This Research Topic is intended to bring together basic researchers and clinicians working in the area of sarcopenia and muscular dystrophy in human and in animal models. The aim of this cross-fertilization is to accelerate understanding of mechanisms involved in aging and dystrophic sarcopenia and to explore the therapeutic potential of pharmacological and nutritional interventions. Contributors are encouraged to submit research articles, reviews, mini-reviews, clinical case study, perspectives, short communications as well as theoretical papers, opinions, and methods.
This Research Topic is intended to bring together basic researchers and clinicians working in the area of sarcopenia and muscular dystrophy in human and in animal models. The aim of this cross-fertilization is to accelerate understanding of mechanisms involved in aging and dystrophic sarcopenia and to explore the therapeutic potential of pharmacological and nutritional interventions. Contributors are encouraged to submit research articles, reviews, mini-reviews, clinical case study, perspectives, short communications as well as theoretical papers, opinions, and methods.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
