Recent Advances in Biodegradable Biomedical Magnesium Alloy

Biomedical implants have been widely applied in clinical practice to replace severely damaged tissues and organs that are seriously missing in structure and function. With the progress of science and technology and the improvement of living standards, patients have higher and higher requirements for implant performance, such as biodegradable absorption, better biocompatibility, mechanical matching and so on. Based on this, biodegradable magnesium (Mg) and its alloy implants emerge as promising candidates such as Mg alloy vascular stent, Mg bone nail, etc. However, the controllable degradation and the adaptation to the lesion tissue are the bottleneck problems in the development and application of biomedical Mg alloys. Therefore, it is very important and meaningful to integrate multi-disciplinary background, such as materials, biology, mechanics, medicine, etc., to provide support for the development of biodegradable Mg alloy implants.

The goal of this Research Topic is to publish research articles and review articles covering the latest studies and progress in different aspects of biodegradable biomedical magnesium (Mg) alloy. Manuscripts that include the systematic research and innovative discovery of Mg and its alloy design, process, evaluation, surface modification and other aspects of Mg alloy implants are welcomed.

Potential topics include but are not limited to the following:
• Design and fabrication techniques of biomedical Mg alloy
• Surface modification
• Degradation mechanism of biomedical Mg alloy
• Biocompatibility of Mg alloy
• Cardiovascular stent, Bone implants, Engineered tissues, Cell signaling for guided tissue regeneration
• Microenvironment for Mg alloy degradation
• Interaction between Mg alloy and cells
• Corrosion resistance of biomedical Mg alloy