Cardiovascular Responses and Diseases at High Altitude

It has been demonstrated that cardiovascular system is one of the earliest responding systems with critical importance at high altitude to compensate the hypoxia stress. There are numerous studies about cardiovascular responses to high altitude hypoxia, such as, the insufficient or excessive response of cardiovascular system have been reported to be associated with high altitude diseases. Moreover, the injuries of cardiovascular system caused by high altitude or hypobaric hypoxia have also been partially investigated. However, a large part of physiology and pathophysiology of cardiovascular system at high altitude has not been uncovered neither at clinical nor mechanistic level.

This Research Topic aims to provide a forum for researchers to discover the performances and mechanisms of cardiovascular response to high altitude as well as their associations with high altitude related diseases including acute and chronic mountain sickness mountain sickness. Furthermore, both clinical and basic research in cardiovascular system and their roles in high altitude diseases are also welcomed.

We welcome papers covering, but not limited to, the following topics:
1) Systemic circulation at high altitude.
2) Pulmonary circulation at high altitude.
3) Cardiac function response to high altitude.
4) Cardiac arrhythmia at high altitude.
5) Prevention of high-altitude diseases.
6) Clinical trial at high altitude.
7) Treatment of high-altitude diseases.
8) Basic research of cardiovascular responses to high altitude or hypoxia.