About this Research Topic
Cancer is ranked as the second death cause, resulted in 9.56 million deaths in 2017 globally.
Although surgery can eliminate about 50% of tumors, lymph node metastasis and distant metastasis are the crucial factors for treatment and outcomes of cancer patients. To treat cancer, especially metastatic metastasis, chemotherapeutics, radiation, and molecularly target drugs are still the backbones. However, the unfavorable side effects of chemotherapeutics and radiation, the high cost of targeted drugs stimulated the enthusiasm for developing novel adjuvant and/or therapeutic agents with better safety profiles and/or low cost.
In this Research Topic, we will focus on novel therapeutic targets in solid tumors. The aim is to collect original researches ranging from novel drug target identification to robust preclinical bases for new therapeutic modalities and drug development, as well as innovative technologies aimed at improving cancer patient's living quality.
We welcome submissions of Original Research, Mini Review, and Review articles that cover areas including but not limited to:
• Discovery and preclinical development of novel natural products/synthetic small organic molecules in relation to solid cancer
• Discovery and development of new cancer drug target
• New macromolecule therapeutics, primarily (but not exclusively) antibodies and antibody-drug conjugates
• Nanomedicine and biomaterial/device for solid tumor treatment
Although surgery can eliminate about 50% of tumors, lymph node metastasis and distant metastasis are the crucial factors for treatment and outcomes of cancer patients. To treat cancer, especially metastatic metastasis, chemotherapeutics, radiation, and molecularly target drugs are still the backbones. However, the unfavorable side effects of chemotherapeutics and radiation, the high cost of targeted drugs stimulated the enthusiasm for developing novel adjuvant and/or therapeutic agents with better safety profiles and/or low cost.
In this Research Topic, we will focus on novel therapeutic targets in solid tumors. The aim is to collect original researches ranging from novel drug target identification to robust preclinical bases for new therapeutic modalities and drug development, as well as innovative technologies aimed at improving cancer patient's living quality.
We welcome submissions of Original Research, Mini Review, and Review articles that cover areas including but not limited to:
• Discovery and preclinical development of novel natural products/synthetic small organic molecules in relation to solid cancer
• Discovery and development of new cancer drug target
• New macromolecule therapeutics, primarily (but not exclusively) antibodies and antibody-drug conjugates
• Nanomedicine and biomaterial/device for solid tumor treatment
Keywords: Cancer therapeutics, Solid Tumor, Synthetic small molecules, Biomacromolecules, Nanomedicine
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
