About this Research Topic
On the other hand, more conventional approaches to achieve weight control are setting up an exercise program, regulating eating habits and behavior management, weight-loss medicines and bariatric surgery among many others.
Diabetes has ranked 15th among the leading worldwide causes of early death in 2016, and notably predictions indicate that this ranking will likely change, and diabetes will rise to seventh place by 2040. According to WHO data, more than 1 million people die every year from obesity related diseases and complications. Therefore, in order to improve the management of obesity and diabetes, the discovery of new and diverse therapeutic agents is becoming more and more crucial.
The aim of this Topic is showcase in vitro and in vivo studies on novel natural compounds being developed for therapeutic to manage diabetes and weight control in order to evaluate and better understand the structure-activity relationships behind these natural compounds and their potential to serve as new therapeutic targets.
With this Research Topic, we welcome submission of Original Research and Review articles that investigate the use of natural compounds targeting weight control and diabetes treatment, including but not limited to the following topics:
• Antidiabetic potentials (in vivo, in vitro activity models and clinical trials) of natural compounds.
• Antiobesity activity (in vivo, in vitro activity models and clinical trials) of natural compounds.
• Synthesis procedures of potential natural antidiabetic or anti-obesity compounds.
• Elucidating the mechanism of action.
• Structure-activity relationship.
• Drug designing studies.
• Molecular docking studies that also include an experimental component.
Important note: All manuscripts submitted to this collection will need to follow the Guidelines for the conception/peer-review of submissions of the Experimental Pharmacology and Drug Discovery Section. Studies carried out with crude extracts/multiherbal preparations or Original Research based solely on in silico techniques will not be considered for review.
Keywords: Diabetes, obesity, molecular docking, natural compound, weight control
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.