About this Research Topic
Immune reactions across living organisms, from plants to human beings, have the primary aim to eliminate possible dangers and to adapt to a change in the environment. It is important to gain an additional understanding of how immunity is influenced by pollutants. The goal of this Research Topic is to help fill gaps in our knowledge about the action of mixtures between pollutants on a variety of organisms, from plants to humans. The collection assembled here will thus shed light on the impact of combined exposure to nanoparticles and other biological or chemical pollutants on the immunity of humans and environmental species.
This Research Topic welcomes Original Research, Review, Perspective, and Opinion articles that consider the impact of combined exposure on the immunity of human beings and environmental species, focussing on (but not limited to) the following aspects:
• Changes in the physical-chemical characteristics of nano- and micro-particles upon interaction with chemical pollutants;
• Realistic biological models for assessing mixtures with respect to the immune effects of combination exposure;
• Correspondence between in vivo and in vitro assessment in terms of dose and effect (molecular endpoints vs. overall effects);
• Immune effects in plants;
• Immune effects in invertebrates;
• Immune effects in vertebrates and human beings (with effects on innate and adaptive immunity);
• Computational approaches to prediction of individual or combined exposure impacts on immune responses;
• Harmonisation of data generation and analysis for regulatory purposes.
Detailed information on the article types available can be found here.
Keywords: Immunotoxicity, pollutant mixtures, particles, chemicals, biotic pollutants, abiotic pollutants, environmental organisms, humans, nanomaterials, nanoparticles, microparticles
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.