About this Research Topic
Hypertension is a growing public health problem worldwide. It is remains highly prevalent, undertreated and uncontrolled. Treatment for hypertension has low efficacy and major complications of uncontrolled hypertension can cause organ damage, particularly in the cardiovascular system. Genetics, inflammation, environmental factors as well as eating habits all influence the onset of hypertension. Though, there are several treatments available such as some of anti-hypertensive medication. The most effective treatment for high blood pressure and hypertension-associated cardiovascular disease is yet to be found.
Renin-angiotensin system inhibitors, calcium channel blockers, beta receptor blockers and diuretics, have been demonstrated to have some preclinical and clinical efficacy, however the underlying mechanisms which cause hypertension have not been fully understood yet. The main aim of this Research Topic is to increase the understanding behind the mechanisms of humoral and nervous regulation on hypertension, and explore novel therapeutic targets to combat hypertension and associated cardiovascular diseases. In addition, this topic will summarize and contrast the current state of the mechanisms and therapy for hypertension to improve the efficiency of existing drugs.
We invite authors to submit research focused on investigating new mechanisms implicated in the high blood pressure and hypertension pathogenesis and progression of organ damage. We welcome high-quality manuscripts on advanced research in vivo and in vitro at functional and molecular levels, with use of both physiological and pharmacological approaches to evaluate experimental and clinical perspectives to combat adverse high blood pressure and hypertension-associated cardiovascular diseases. Topics of interest include, but are not limited to:
- The mechanism of sympathetic and parasympathetic nerves on the regulation of hypertension
- Signaling pathways involved in the progression of hypertension and cardiovascular diseases
- G protein-coupled receptors in hypertension and cardiovascular diseases
- Hypertension in pregnancy
- Pulmonary hypertension treatment
Renin-angiotensin system inhibitors, calcium channel blockers, beta receptor blockers and diuretics, have been demonstrated to have some preclinical and clinical efficacy, however the underlying mechanisms which cause hypertension have not been fully understood yet. The main aim of this Research Topic is to increase the understanding behind the mechanisms of humoral and nervous regulation on hypertension, and explore novel therapeutic targets to combat hypertension and associated cardiovascular diseases. In addition, this topic will summarize and contrast the current state of the mechanisms and therapy for hypertension to improve the efficiency of existing drugs.
We invite authors to submit research focused on investigating new mechanisms implicated in the high blood pressure and hypertension pathogenesis and progression of organ damage. We welcome high-quality manuscripts on advanced research in vivo and in vitro at functional and molecular levels, with use of both physiological and pharmacological approaches to evaluate experimental and clinical perspectives to combat adverse high blood pressure and hypertension-associated cardiovascular diseases. Topics of interest include, but are not limited to:
- The mechanism of sympathetic and parasympathetic nerves on the regulation of hypertension
- Signaling pathways involved in the progression of hypertension and cardiovascular diseases
- G protein-coupled receptors in hypertension and cardiovascular diseases
- Hypertension in pregnancy
- Pulmonary hypertension treatment
Keywords: Hypertension, Cardiovascular diseases, Humoral regulation, Nervous regulation
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
