The Arbovirus Profiles and Interactions with Hosts – Preparing for Emerging Diseases

Arthropods, like ticks and mosquitoes, carry a huge community of highly genetically diverse viruses. Previous studies have reported the identification and isolation of novel arboviruses from ticks and mosquitoes, suggesting that arbovirus population diversity may be far beyond our current understanding. Arboviruses can be transmitted from arthropods to hosts through blood-feeding, dependent upon virus properties such as host entry and interaction and subsequent host responses to eliminate viruses. So far, many arboviruses have been identified as causative agents of human diseases, suggesting they could pose a threat to public health. To further our understanding of arbovirus transmission and develop disease control measures, it is important to survey the distribution and evolution of pathogenic arboviruses and investigate interactions between viruses and hosts. Moreover, the discovery of novel arboviruses and the identification of potential threats can help facilitate early preparation and provide treatment to emerging diseases.

This Research Topic will provide an overview of the arbovirus community and further understand arbovirus interactions with hosts. It will also help identify potential threats from emerging arboviruses and fill in current knowledge gaps surrounding early preparation for emerging disease control measures.

Original Research Articles, Reviews, Methods and Perspectives focusing on the following subtopics will be considered:
• Profiling viruses from arthropods
• Discovering novel viral pathogens from arthropods
• Epidemiology, spatial and temporal distribution, and evolution of arboviruses
• Molecular mechanisms of arbovirus infection and replication in hosts
• Arbovirus pathogenesis in hosts