About this Research Topic
An understanding of disease mechanisms at cellular and molecular levels is needed. The boosting of host immune responses and provision of sustained or effective immunity are key factors in the prevention of microbial infections or diseases. Therefore, the aim of this Research Topic is to recapitulate and collate relevant, recent data regarding zoonotic diseases of global importance and to decipher basic immunopathogenesis mechanisms. Especially now, during the COVID-19 pandemic, it is of utmost importance to explore zoonotic aspects (spillover, transmission dynamics, contagiousness, reservoir hosts), virus-host interactions, and immunogenicity.
This Research Topic aims to cover basic and applied aspects of zoonotic diseases, with a special focus on viral human diseases and their immunopathogeneses. We especially aim to cover:
• Molecular epidemiology of zoonotic viral infections (e.g., Influenza, SARS, MERS and COVID-19) of public or global health importance;
• The evolution and adaptation of zoonotic viruses, in the context of One Health;
• Receptor-mediated spillover events and zoonotic potential of the Influenza, SARS, MERS and SARS-CoV-2 viruses;
• Tissue tropisms and inter-species jump of Influenza, SARS, MERS, and SARS-CoV-2 viruses;
• Immunopathogenesis (host-pathogen interaction), immuno-surveillance and immune evasion of viral infections.
The following article types are welcome: Original research, Review, Mini-Review, Commentary.
Keywords: Infectious diseases, epidemics, One Health
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.