About this Research Topic
In recent decades, biomaterials with nanoscaled structures have demonstrated to possess versatile performances due to their tunable physical, chemical, and biological properties. Both chemical composition and structure have profound impact on the bioactivities of the materials, that nanostructured biomaterials can regulate biological processes by interacting with biomolecules, cells and tissues. This impact has been drawing significant interest for emerging biomedical fields such as tissue engineering, theranostics, drug delivery, biosensing, stem cell and antibacterial agents. Therefore, it is of great importance to explore novel nanomaterials with rational design and preparation techniques to meet various needs in these different biomedical applications.
One major challenge of current biomaterial research is the controlled regulation of biological events via the presence of material due to the limited understanding of material-bio interactions. Previous studies on nanostructured biomaterials include a "cook-and-look" process, which involves synthesis of nanomaterials and check their biological effects. With the increasing knowledge on how biological substances respond to nanomaterials, it allows us to actively design and fabricate the desired nanostructures. Over the years, with the aid of chemical methods, researchers can solve some biomedical problems by engineering nano-based platform in translational and clinical settings, pushing the frontiers of biomaterials forward.
In this topic, we aim to cover recent research in nanostructured materials for biomedical applications. The nanostructures here should be designed and prepared in a rational manner. We welcome submissions of Original Research, Review, Mini Review and Perspective articles. This topic on “Rational Design and Preparation of Nanostructured Biomaterials” covers, but are not limited to, the following themes:
• Design of nanostructured interface for control of cell fate
• Fabrication of 3D scaffolds with nanofeatures for tissue regeneration
• Design and preparation of nanocarriers for smart drug delivery
• Advances in chemical methods for novel bioactive nanostructures
• Biological microenvironment-driven nanoreactors
• Current development of nanostructured biomaterials and future perspectives
Keywords: nanostructure; biomaterials; chemical synthesis; biointerface; nanomedicine;
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
