Metabolism and Vascular Diseases

Vascular disease is now the leading cause of death worldwide, with cardiovascular and cerebrovascular diseases being the main contributors. However, its pathological mechanism is not definite yet. Currently, various kinds of vascular diseases are supposed to be related to metabolic disturbance. Generally, specific vascular disease indicates a disorder in the whole circulatory system. The systemic metabolic disturbance would result in various kinds of pathologic changes in the circulatory system and undermine vascular homeostasis, involve atherosclerosis, vascular remodeling, etc. Meanwhile, cellular metabolism makes a strong bond with the local vascular lesion, like atheromatosis, endothelium injury, etc. However, the metabolic balance would also be affected by local vascular cells' physiological regulation, vascular development, and haemodynamics. The characterisation of metabolic disturbance and related vascular diseases involves many events and complicated connections, which leave quite a lot of gaps in the field to be further studied.

This Research Topic aims to cover promising and novel research trends in metabolism and related vascular diseases.

Areas to be covered in this Research Topic may include, but are not limited to:
• Effect of cell metabolism on Atherosclerosis/Vascular Remodeling/Endothelial Injury
• Connection of systemic metabolic disturbance with Vascular Diseases
• Gut Flora and Vascular Diseases
• Impact of pathological vascular homeostasis on systemic metabolism/regional cell metabolism

We welcome submissions of several article types, including original research articles and reviews.