About this Research Topic
The aim of this Research Topic is to highlight the complex diversity of astrocytes and microglia and its impact on the function or dysfunction of neural circuits, neurons and glia in the CNS. Advances in the discovery of astrocyte and microglia diversity could facilitate the design of targeted therapeutic strategies to improve the outcomes of CNS pathologies.
For this Research Topic, we invite original articles and reviews in the research areas including but not limited to
-The ontogeny of astrocyte and microglia heterogeneity.
- The regional characteristics of astrocytes and microglia in the healthy, aging, diseased and injured CNS.
- Intra-regional diversity of astrocyte and microglia subpopulations.
- The impact of astrocyte and microglia heterogeneity on the function or dysfunction of specific neuronal circuits in the CNS.
- The disease-specific properties and functional diversity of astrocytes and microglia in neurodegenerative and inflammatory diseases, psychiatric and mood disorders, brain and spinal cord injuries, developmental disorders of the CNS, neuropathic pain and other CNS pathologies.
- Commonalties in the determinants of the phenotypic and functional diversity of astrocytes and microglia across different CNS pathologies.
Keywords: Heterogeneity, Injury, Neurodegeneration, Neuroprotection, Regeneration
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.